Investigation of factors affecting spontaneous ureteral stone excretion

IF 0.2 Q4 UROLOGY & NEPHROLOGY Journal of Renal Injury Prevention Pub Date : 2021-10-15 DOI:10.34172/jrip.2022.17691
M. Abedinzadeh, H. Karami, J. Gholami, H. Maleki
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Abstract

Introduction: Various factors such as structure of stone, size, location of stone and metabolic diseases affect stone excretion. Objectives: The aim of this study was to investigate factors related to spontaneous ureteral stone excretion. Patients and Methods: This descriptive-analytical observational study was conducted in the university urology centers of Yazd, Iran, during a 16-month period. All patients presenting with unilateral ureteral stone whose ureteral stone was confirmed by CT scan or ultrasound were included in the study. Pregnant patients, patients with uncontrolled hypertension, patients with multiple urinary stones, patients with more than four weeks of history of urinary stones, patients with severe hydronephrosis, and patients with malformations of ureter and kidney were excluded from the study. Computed tomography and ultrasound of the patients evaluated the size of the stone, the location of the stone and the degree of hydronephrosis and also perinephric stranding. Results: In this study, 146 patients with mean age of 45.3±15.1 years (ranging from 11 to 84 years) were enrolled. CT scan and ultrasound were diagnostic in 121 (82.9%) and 25 patients (17.1%) respectively. In logistic regression model analysis, size less than 5mm, stone location and male gender and diabetes were significant predictors of spontaneous stone excretion, while size less than 5 mm was the strongest predictor. Conclusion: The strongest predictor of spontaneous excretion is the size of the stone and the next step is the location of the stone. Male gender and diabetes are also contributing factors to the spontaneous excretion of ureteral stones.
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影响输尿管结石自发排泄的因素探讨
引言:结石的结构、大小、位置和代谢性疾病等多种因素会影响结石的排泄。目的:本研究旨在探讨输尿管结石自发排泄的相关因素。患者和方法:这项描述性分析观察性研究在伊朗亚兹德大学泌尿外科中心进行,为期16个月。所有表现为单侧输尿管结石且经CT扫描或超声证实为输尿管结石的患者均纳入研究。妊娠患者、未控制的高血压患者、多发性尿路结石患者、尿路结石病史超过四周的患者、严重肾积水患者以及输尿管和肾脏畸形患者均被排除在研究之外。患者的计算机断层扫描和超声波评估了结石的大小、结石的位置、肾积水的程度以及肾周绞窄。结果:本研究共纳入146例患者,平均年龄45.3±15.1岁(11至84岁)。CT和超声分别诊断121例(82.9%)和25例(17.1%)。在逻辑回归模型分析中,结石大小小于5mm、结石位置、男性和糖尿病是结石自发排泄的显著预测因素,而结石大小小于5 mm是最强的预测因素。结论:自发排泄的最强预测因素是结石的大小,下一步是结石的位置。男性和糖尿病也是导致输尿管结石自发排泄的因素。
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来源期刊
Journal of Renal Injury Prevention
Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-
CiteScore
1.60
自引率
0.00%
发文量
36
期刊介绍: The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.
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