Functionalization of Titanium Surfaces with Lysine: A Micro Raman Study of the Intermolecular Interactions of Lysine-TiO2

IF 2.4 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Journal of Molecular and Engineering Materials Pub Date : 2018-09-01 DOI:10.1142/S2251237318500077
Cesar A. Manrique-Bastidas, P. Sundaram, P. Resto, N. Mina-Camilde, S. Hernández‐Rivera
{"title":"Functionalization of Titanium Surfaces with Lysine: A Micro Raman Study of the Intermolecular Interactions of Lysine-TiO2","authors":"Cesar A. Manrique-Bastidas, P. Sundaram, P. Resto, N. Mina-Camilde, S. Hernández‐Rivera","doi":"10.1142/S2251237318500077","DOIUrl":null,"url":null,"abstract":"Raman scattering (RS) was used as a powerful, efficient, and sensitive technique for studying intermolecular interactions between an organic ligand adsorbate and a metallic substrate. Functionalization of titanium (TiO2[Formula: see text]Ti) surfaces was performed using lysine (Lys) as adsorbate and later developing a hydroxyapatite (HA) layer onto this functionalized surface. The functionalization process was performed at different pH values of the interacting chemical species. Chemisorption onto the TiO2Ti substrates through the Lys carboxylic group was demonstrated spectroscopically. Analysis of vibrational spectra showed that the CH side chain of Lys was relatively distant from the (TiO2[Formula: see text]Ti) surface, preventing direct contact with the surface. Additionally, the signals corresponding to the unbound [Formula: see text]-NH2 group indicate that it is available for additional complexation. In vitro bioactivity of the Lys–TiO2[Formula: see text]Ti surface was achieved by developing an HA layer onto already functionalized TiO2[Formula: see text]Ti surfaces at various pH values. Spectroscopic data using the spectral markers of HA and Lys provided a decisive role in establishing the necessary baseline data for evidencing the intermolecular bonding. The functionalized TiO2[Formula: see text]Ti surface reactivity is linked to the specific intermolecular interactions of –COO− (pH 7.0) with Ca[Formula: see text] ions, as well as the –COOH (pH 2.0 and 12.0) groups of Lys, with the –OH groups of PO[Formula: see text] belonging to HA.","PeriodicalId":16406,"journal":{"name":"Journal of Molecular and Engineering Materials","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1142/S2251237318500077","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Molecular and Engineering Materials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/S2251237318500077","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Raman scattering (RS) was used as a powerful, efficient, and sensitive technique for studying intermolecular interactions between an organic ligand adsorbate and a metallic substrate. Functionalization of titanium (TiO2[Formula: see text]Ti) surfaces was performed using lysine (Lys) as adsorbate and later developing a hydroxyapatite (HA) layer onto this functionalized surface. The functionalization process was performed at different pH values of the interacting chemical species. Chemisorption onto the TiO2Ti substrates through the Lys carboxylic group was demonstrated spectroscopically. Analysis of vibrational spectra showed that the CH side chain of Lys was relatively distant from the (TiO2[Formula: see text]Ti) surface, preventing direct contact with the surface. Additionally, the signals corresponding to the unbound [Formula: see text]-NH2 group indicate that it is available for additional complexation. In vitro bioactivity of the Lys–TiO2[Formula: see text]Ti surface was achieved by developing an HA layer onto already functionalized TiO2[Formula: see text]Ti surfaces at various pH values. Spectroscopic data using the spectral markers of HA and Lys provided a decisive role in establishing the necessary baseline data for evidencing the intermolecular bonding. The functionalized TiO2[Formula: see text]Ti surface reactivity is linked to the specific intermolecular interactions of –COO− (pH 7.0) with Ca[Formula: see text] ions, as well as the –COOH (pH 2.0 and 12.0) groups of Lys, with the –OH groups of PO[Formula: see text] belonging to HA.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
赖氨酸对钛表面的功能化:赖氨酸-TiO2分子间相互作用的显微拉曼研究
拉曼散射(RS)是一种强大、高效、灵敏的技术,用于研究有机配体吸附质和金属基质之间的分子间相互作用。使用赖氨酸(Lys)作为吸附质进行钛(TiO2[式:见正文]Ti)表面的功能化,随后在该功能化表面上形成羟基磷灰石(HA)层。官能化过程在相互作用的化学物质的不同pH值下进行。通过光谱证明了Lys羧基在TiO2Ti衬底上的化学吸附。振动光谱分析表明,Lys的CH侧链与(TiO2[公式:见正文]Ti)表面相对较远,防止与表面直接接触。此外,与未结合的[公式:见正文]-NH2基团相对应的信号表明它可用于额外的络合。Lys–TiO2[公式:见正文]Ti表面的体外生物活性是通过在不同pH值下在已经官能化的TiO2[配方:见正文]Ti表面上形成HA层来实现的。使用HA和Lys的光谱标记的光谱数据在建立证明分子间键合的必要基线数据方面发挥了决定性作用。功能化的TiO2[式:见正文]Ti表面反应性与–COO−(pH 7.0)与Ca[式:参见正文]离子的特定分子间相互作用以及Lys的–COOH(pH 2.0和12.0)基团有关,PO的–OH基团[式:详见正文]属于HA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of Molecular and Engineering Materials
Journal of Molecular and Engineering Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-
自引率
0.00%
发文量
13
期刊最新文献
Identification of object roughness using a flexible capacitive 3D force transducer featuring an interlocking microstructure Applications of marker assisted gene pyramiding in rice crop improvement Green Synthesis of Copper Nanoparticles Using Flower Extracts: A Promising Route for Enhanced Microelectronics Packaging Characterization of RF-Sputtered ZnO Thin film Coatings on Aluminium (Al6061): Microstructure, Wettability, Cavitation, and Corrosion Analysis Molecular Docking and Ligand-Binding Analysis of Amidine Derivatives Targeting Pseudomonas Aeruginosa and Escherichia Coli Bacterial Strains: An in Silico Approach
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1