Surgical Outcomes of Three Repair Techniques for Partial Anomalous Pulmonary Venous Connection in Adult Patients

Aleksander Dokollari, M. Cameli, M. Maccherini, Haxhire Kafazi, A. Veshti, S. Sicouri, M. Bonacchi
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Abstract

Objectives: To investigate primary and secondary surgical outcomes following transcaval repair (TCR), modified Warden repair, and transatrial repair techniques for partial anomalous pulmonary venous connections (PAPVCs) and sinus venosus atrial septal defects (ASDs). Methods: This is an observational cohort clinical study. Patients who underwent TCR, modified Warden repair, and transatrial surgical repair for PAPVC and ASD between January 2003 and October 2019 at our institution were included in the study. Patients had one of the surgical procedures based on the anatomy of the defect. Results: Ten patients, seven (70%) males and three (30%) females, were included in the analysis. Seven patients underwent TCR, two patients the modified Warden technique, and one patient underwent transatrial surgical repair. Mean age was 57 years ± 14.7. Mean EuroScore II was 3.4 ± 3.5. The baseline left ventricle ejection fraction was 45 ± 6.5%. No patient had previous stroke, pacemaker (PM) implantation, or myocardial infarction. Total cardiopulmonary bypass and cross-clamping time were 123 ± 72.5 and 100 ± 48.5 min, respectively. Mean mechanical ventilation, mean intensive care unit, and mean hospital length of stay for the transcaval, modified Warden, and transatrial groups were 4.6 ± 10.7, 5.7 ± 8.8, and 10.5 ± 9.2 days, respectively. Superior caval or pulmonary venous obstruction, sinus node dysfunction, and PM implantation were not present at follow-up. The patient who underwent transatrial repair had died at 5.5-year follow-up due to myocardial infarction. Total survival rate at 6 years was 90%. Conclusions: The findings from this study elicit that all three techniques have low postoperative morbidity and are feasible and reliable procedures.
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三种修复技术治疗成人部分异常肺静脉连接的手术效果
目的:研究经腔修补术(TCR)、改良Warden修补术和经心房修补术治疗部分异常肺静脉连接(PAPVC)和静脉窦性房间隔缺损(ASD)后的一次和二次手术结果。方法:这是一项观察性队列临床研究。2003年1月至2019年10月期间在我们机构接受了PAPVC和ASD TCR、改良Warden修复和经试验手术修复的患者被纳入研究。患者根据缺损的解剖结构进行了一次手术。结果:10名患者,7名(70%)男性和3名(30%)女性被纳入分析。7名患者接受TCR,2名患者接受改良Warden技术,1名患者接受经试验手术修复。平均年龄57岁±14.7岁。平均EuroScore II为3.4±3.5。基线左心室射血分数为45±6.5%。没有患者既往发生过中风、起搏器(PM)植入或心肌梗死。体外循环和交叉夹闭时间分别为123±72.5和100±48.5分钟。经阴道、改良Warden和经阴道试验组的平均机械通气、平均重症监护室和平均住院时间分别为4.6±10.7、5.7±8.8和10.5±9.2天。随访时未发现上腔静脉或肺静脉阻塞、窦房结功能障碍和PM植入。接受跨试验修复的患者在随访5.5年时死于心肌梗死。6年总生存率为90%。结论:这项研究的结果表明,这三种技术的术后发病率都很低,是可行和可靠的手术方法。
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