Management of Giant Cell Tumors in Hand and Foot.

IF 0.6 Q4 ONCOLOGY Indian Journal of Surgical Oncology Pub Date : 2024-03-01 Epub Date: 2020-08-01 DOI:10.1007/s13193-020-01153-z
Coşkun Ulucaköy, İsmail Burak Atalay, Recep Öztürk, Aliekber Yapar, Yaman Karakoç
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Abstract

The aim of this study is to determine the treatment modalities and clinical characteristics of 12 patients diagnosed with giant cell tumor (GCT) of the hand and foot. The clinical findings, treatment modalities, and treatment failures of 12 patients with giant cell tumors of the hand and foot bones between 2007 and 2018 years were evaluated retrospectively. The average age at diagnosis was 29.2 ± 14.9 std. (between 16 and 62 years old), 8 males (66.6%) and 4 females (33.3%). Tumor was more frequently located in the talus, metacarpal, and metatarsal bones. The mean tumor size was 3.1 ± 1.1 cm (between 2.2 and 5.3 cm). The mean post-operative follow-up period was 76.3 ± 42.5 (between 12 and 139 months). The most of patients' (58.3%) common complaints were pain. The most commonly used surgical method was curettage + autografting (91.7%). Infection was seen in one patient after relapse surgery. Recurrence occurred in 33.3% of the patients in the first year. Only one patient was detected to have knee and lung metastases. Swelling and pain in the hand and foot should be examined for tumor lesions. When a bone lesion is detected, the giant cell tumor of the bone should be included in the differential diagnosis. Patients with giant cell tumors should be followed closely for recurrence and metastasis after treatment.

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手足巨细胞瘤的治疗
本研究旨在确定12名确诊为手足骨巨细胞瘤(GCT)患者的治疗方式和临床特征。研究对2007年至2018年间12例手足骨巨细胞瘤患者的临床表现、治疗方式和治疗失败情况进行了回顾性评估。确诊时的平均年龄为(29.2±14.9)岁(16至62岁之间),其中男性8人(66.6%),女性4人(33.3%)。肿瘤多位于距骨、掌骨和跖骨。肿瘤平均大小为 3.1 ± 1.1 厘米(2.2 至 5.3 厘米)。术后平均随访时间为 76.3 ± 42.5(12 至 139 个月)。大多数患者(58.3%)的主诉是疼痛。最常用的手术方法是刮除+自体移植(91.7%)。一名患者在复发手术后出现感染。33.3%的患者在第一年内复发。只有一名患者被发现有膝盖和肺部转移。应检查手部和足部的肿胀和疼痛是否为肿瘤病变。当发现骨病变时,应将骨巨细胞瘤纳入鉴别诊断。巨细胞瘤患者在治疗后应密切观察复发和转移情况。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
190
期刊介绍: The Indian Journal of Surgical Oncology aims to encourage and promote clinical and research activities pertaining to Surgical Oncology. It also aims to bring in the concept of multidisciplinary team approach in management of various cancers. The Journal would publish original article, point of technique, review article, case report, letter to editor, profiles of eminent teachers, surgeons and instititions - a short (up to 500 words) of the Cancer Institutions, departments, and oncologist, who founded new departments.
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