Genetic Diversity and Comprehensive Phylodynamic Analysis of Whole Corona Viruses Genomes

Abstract

Covid-19 is a rapidly emerging viral respiratory disease The infection of corona virus disease (COVID-19) is initiated by the strains of severe acute respiratory syndrome Corona virus 2 (SARS-CoV-2), is a highly transmittable viral infection that was first emerged in the of Wuhan, a city of China and ultimately extent in whole world The World health organization (WHO) affirmed this infection as a global public health disaster Genomic analysis showing that this novel SARSCoV-2 is hereditarily linked with severe acute respiratory syndrome-like (SARS-like) bat viruses indicating that bats might be the primary source of this epidemic infection In this review we have summarized a comprehensive phylodynamic analysis of whole corona virus genome sequences in order to analyze the pathogenicity and emergence of novel COVID-19 infection and previous human coronaviruses Our main objective is to describe the genetic relationships of the 2019-nCoV with other genera of coronavirus and to find out supposed recombination contained by sarbecovirus subgenus