The Risk of Subsidence in Standalone Oblique Lumbar Interbody Fusion: A 12-Month Follow-Up Prospective Study

Mohamed K. Elkazaz, A. Abou-Madawi, Hassan A. Alshatoury, Mohamed Alqazaz, A. Abdelmoneam, K. Salem
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Abstract

Background data: The incidence of interbody cage subsidence in oblique lumbar interbody fusion (OLIF) is 8 e 9.5%. It occurs mainly secondary to osteoporosis or end-plate damage during disk space clearance. An anatomical study correlated the surface area contact and position between the cage and the disk space to the incidence of subsidence. Studies have concentrated on the optimal place in the disk space to place the cage to obtain less incidence of subsidence, as it was reported that the central part of the disk space, called the epiphyseal ring, is the toughest part. Subsidence is usually noted in the superior vertebral end plate. Until now, there has been a lack of data regarding the main cause of subsidence. Study design: This is a prospective, clinical case study. Objective: This study aims to assess the subsidence rate in patients undergoing standalone (SA)-OLIF for degenerative lumbar diseases. Patients and methods: Patients with adult degenerative scoliosis following speci fi c inclusion criteria underwent SA-OLIF. The following data were all analyzed and compared statistically: preoperative and postoperative clinical data; back and leg pain visual analog score (VAS) and Oswestry disability index; radiological data; spinopelvic parameters, segmental Cobb ' s angle and anterior disk height, and intraoperative data; operative time; the amount of blood loss; complications (intraoperative or postoperative); and hospital stay. Results: A total of 28 patients and 30 levels were operated on by SA-OLIF, with a mean age of 50.54 ± 6.05, including 14 males and 14 females. The mean operative time/min, blood loss, and hospital stay/day was 91.29 ± 14.23, 195.54 ± 42.299, and 2.78 ± 0.875, respectively. The mean of back pain VAS, the mean of leg pain VAS, and Oswestry disability index changed from preoperatively 7.36 ± 0.98, 6.36 ± 0.911, and 53.71 ± 18.9 to 4.07 ± 1.01, 2.07 ± 0.9, and 45.25 ± 18.76 in 1 year, respectively. Fusion rates were assessed at 6 and 12 months by multislice computed tomography. During the 6-month follow-up period, 83.3% (25 levels) of grade I and grade II fusion was interpreted as solid fusion and 6.6% as cage subsidence (two levels), and during the 12-month follow-up, 89.9% (27 levels) as grade I and grade II fusion and 6.6% cage subsidence (two levels). Conclusion: Subsidence in SA-OLIF highly contributed to end-plate injury during the surgery and osteoporosis; consequently, posterior instrumentation is advised in these patients along with OLIF to decrease the subsidence rate.
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独立斜腰椎体间融合术中下沉的风险:一项为期12个月的随访前瞻性研究
背景资料:斜腰椎体间融合术(OLIF)椎间笼沉降发生率为89.5%。它主要继发于骨质疏松症或椎间盘间隙清除期间的终板损伤。一项解剖学研究将笼和椎间盘空间之间的表面积接触和位置与沉降的发生联系起来。研究集中在椎间盘空间中放置笼的最佳位置,以获得较少的下沉发生率,因为据报道,椎间盘空间的中心部分,称为骨骺环,是最坚硬的部分。下陷通常发生在上部椎体终板。到目前为止,一直缺乏有关下沉主要原因的数据。研究设计:这是一项前瞻性临床病例研究。目的:本研究旨在评估腰椎退行性疾病行独立(SA)-OLIF患者的沉降率。患者和方法:符合特定纳入标准的成人退行性脊柱侧凸患者接受了SA-OLIF。对以下资料进行统计分析比较:术前、术后临床资料;背部和腿部疼痛视觉模拟评分(VAS)和Oswestry残疾指数;辐射数据;脊柱骨盆参数、节段Cobb角、前盘高度及术中数据;手术时间;失血量;并发症(术中或术后);还有住院。结果:共行SA-OLIF手术28例,30个节段,平均年龄50.54±6.05岁,其中男14例,女14例。平均手术时间/min 91.29±14.23,出血量195.54±42.299,住院天数2.78±0.875。1年内腰痛VAS均值、腿痛VAS均值、Oswestry失能指数分别由术前的7.36±0.98、6.36±0.911、53.71±18.9变化为4.07±1.01、2.07±0.9、45.25±18.76。6个月和12个月时通过多层计算机断层扫描评估融合率。在6个月的随访期间,83.3%(25个节段)的I级和II级融合为固体融合,6.6%为笼沉降(2个节段);在12个月的随访期间,89.9%(27个节段)为I级和II级融合,6.6%为笼沉降(2个节段)。结论:手术中SA-OLIF的下沉是导致终板损伤和骨质疏松的重要原因;因此,建议这些患者在OLIF的同时进行后路内固定以减少下沉速率。
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