Cortical sparing adrenalectomy in sporadic and bilateral tumors

D. Colleselli, G. Janetschek
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引用次数: 2

Abstract

Complete removal of the adrenal gland has been the standard approach in the surgical treatment of tumors for decades. There, however, is bigger role emerging for organ sparing adrenalectomy especially in the era of minimal invasive surgery. Initially proposed for bilateral tumors in hereditary diseases and in tumors in a solitary gland, partial adrenalectomy gained also popularity in the treatment of spontaneous unilateral small masses. Various surgical techniques have been described so far with promising surgical and functional outcomes with increased quality of life compared to total adrenalectomy. Steroid replacement can be avoided in most cases even in bilateral disease and successful normalization of pathological preoperative endocrine levels were reported in various kinds of adenoma. Therefore, minimal invasive partial adrenalectomy, which seems to be still underused, is a valid treatment option for small hormonal active adrenal tumors whenever surgically possible.
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保留肾上腺皮质切除术治疗散发性和双侧肿瘤
几十年来,完全切除肾上腺一直是肿瘤外科治疗的标准方法。然而,保留器官的肾上腺切除术正在发挥更大的作用,尤其是在微创手术时代。肾上腺部分切除术最初被提出用于治疗遗传性疾病中的双侧肿瘤和孤立腺肿瘤,在治疗自发性单侧小肿块方面也很受欢迎。到目前为止,已经描述了各种手术技术,与全肾上腺切除术相比,这些技术具有良好的手术和功能效果,提高了生活质量。在大多数情况下,即使在双侧疾病中也可以避免类固醇替代,并且据报道,在各种腺瘤中,术前病理内分泌水平成功正常化。因此,微创肾上腺部分切除术(似乎仍未得到充分利用)是一种有效的治疗方案,只要有手术可能,就可以治疗激素活性小的肾上腺肿瘤。
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