Vitamin E protects rat testis, eye and erythrocyte from oxidative stress during exposure to radiofrequency wave generated by a BTS antenna model

Abstract

Background: Radio frequency wave (RFW) generated by mobile phones and wireless communica on systems has been reported to cause adverse effects on reproduc ve func on, vision and hematological parameters, possibly through oxida ve stress. The aim of this study was to evaluate the effect of RFW generated bybase transceiver sta on BTS on oxida ve stress in tes s, eye and erythrocyte, and the prophylac c effect of vitamin E by measuring the an oxidant enzymes ac vity, including: glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT), and lipid proxida on. Materials and Methods: Thirty-two adult male Sprague–Dawley rats were randomly divided into four groups and treated daily for 45 days as follows: control, treatment control (vitamin E 200 mg/kg of body weight/ day by gavage), sham exposed group (exposed to 900 MHz RFW), and treatment group (received vitamin E and exposed to RFW). Control and treatment control groups were not exposed and were only given the vehicle, i.e., dis lled water. On the last day of the study, all the rats were sacrificed and their testes, eyes and erythrocyte were collected and used for measurement of an oxidant enzymes ac vity and lipid peroxida on. Results: Exposure to RFW in the sham exposed group decreased an oxidant enzymes ac vity and increased lipid peroxida on compared to both control groups (p<0.05). In the treatment group, vitamin E improved an oxidant enzymes ac vity and reduced lipid peroxida on compared to the sham exposed group (p<0.05). Conclusion: RFW causes oxida ve stress in eye, tes s and erythrocytes and vitamin E improved oxida ve stress in these ssues.