Characterization of mesoporous in β-tricalcium phosphate using electron microscopy

Abstract

Abstract

A simple and scalable method, spray drying, for fabricating mesoporous β-tricalcium phosphate (β-TCP) was developed. The spray-dried powders were characterized using X-ray diffraction, Fourier-transform infrared, scanning electron microscope, transmission electron microscope, BET analysis, and in vitro cell viability. The obtained average particle sizes range between 0.3 and 1.8 μm, BET surface areas range between 16 and 64 m²/g, and average pore diameters are 3 nm. Meanwhile, the β-TCP powders exhibited no cytotoxicity except for the 800 ℃. In addition, for porous observation, detailed information on pore morphologies and corresponding pore size distributions was obtained. Finally, the pore formation mechanism of spray-dried β-TCP was discussed.