Assessing the KEMI approach for determining the size of mixture assessment factors needed to protect aquatic receptors from chemical mixtures in surface waters
{"title":"Assessing the KEMI approach for determining the size of mixture assessment factors needed to protect aquatic receptors from chemical mixtures in surface waters","authors":"Paul S. Price , Marion Junghans","doi":"10.1016/j.cotox.2023.100426","DOIUrl":null,"url":null,"abstract":"<div><p>This article discusses the Swedish Chemicals Agency's proposal for estimating the size of a Mixture Assessment Factor (the KEMI MAF) for aquatic mixtures of chemicals. The KEMI MAF is an improvement over earlier approaches but is dependent on factors that are uncertain, such as: the number of chemicals that reach an aquatic receptor, the allocation of chemicals into assessment groups, and the impacts of future regulations on chemical concentrations in water. This article demonstrates that these uncertainties have significant impacts on the size of MAFs required for aquatic receptors. As part of this assessment a simplified method of calculating the KEMI MAF was developed.</p></div>","PeriodicalId":37736,"journal":{"name":"Current Opinion in Toxicology","volume":"36 ","pages":"Article 100426"},"PeriodicalIF":6.1000,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468202023000414","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"TOXICOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This article discusses the Swedish Chemicals Agency's proposal for estimating the size of a Mixture Assessment Factor (the KEMI MAF) for aquatic mixtures of chemicals. The KEMI MAF is an improvement over earlier approaches but is dependent on factors that are uncertain, such as: the number of chemicals that reach an aquatic receptor, the allocation of chemicals into assessment groups, and the impacts of future regulations on chemical concentrations in water. This article demonstrates that these uncertainties have significant impacts on the size of MAFs required for aquatic receptors. As part of this assessment a simplified method of calculating the KEMI MAF was developed.
期刊介绍：
The aims and scope of Current Opinion in Toxicology is to systematically provide the reader with timely and provocative views and opinions of the highest qualified and recognized experts on current advances in selected topics within the field of toxicology. The goal is that Current Opinion in Toxicology will be an invaluable source of information and perspective for researchers, teachers, managers and administrators, policy makers and students. Division of the subject into sections: For this purpose, the scope of Toxicology is divided into six selected high impact themed sections, each of which is reviewed once a year: Mechanistic Toxicology, Metabolic Toxicology, Risk assessment in Toxicology, Genomic Toxicology, Systems Toxicology, Translational Toxicology.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
