Discussion on relationship between meridians and viscera of decreased ovarian reserve from the perspective of “preventive treatment of disease” by acupuncture

IF 4.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE World Journal of Traditional Chinese Medicine Pub Date : 2023-04-01 DOI:10.4103/2311-8571.378173
Sian Pan, Zhimiao Murong, Yi-Lin Zhu, Jia Song, Xiao-rong Chang, Yu Liu, Zenghui Yue
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Abstract

Based on extensive historical data, clinical experience, and modern scientific research, we discuss the relationship between meridians and viscera of decreased ovarian reserve (OR) from the perspective of “preventive treatment of disease” by acupuncture. It is believed that the endogenous protection mechanism of acupuncture in “preventive treatment of disease” lies in harmonizing Yin and Yang and dredging meridians; stimulating righteousness and rejecting the evil outside; preventing disease; co-cultivating body and spirit, and regulating emotions. The incidence of OR dysfunction is closely related to the uterus-related meridians and viscera. The mechanism of acupuncture treatment of OR dysfunction may be related to reproductive endocrine hormone levels, ovarian tissue morphology, immune system, granulosa cell apoptosis, and related signal transduction pathways. The clinical effect of acupuncture treatment of diminished OR is reflected in improving menstruation and ovulation; improving OR function, promoting pregnancy; improving local ovarian microenvironment; improving negative emotions, improving quality of life, and thus affecting pregnancy outcomes. This article summarizes the mechanism of action and clinical effect of acupuncture in the treatment of decreased OR function based on recent findings, analyzes the advantages and disadvantages of acupuncture in the treatment of disease, and provides the rationale for the clinical application of acupuncture in the treatment of decreased OR function.
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从针灸“防病”论卵巢储备减少的经络关系
根据大量的历史资料、临床经验和现代科学研究,我们从针灸“防病治病”的角度探讨了卵巢储备减少的经脉与脏器之间的关系。认为针灸在“防病治病”中的内生保护机制在于调和阴阳、疏通经络;激扬正气,拒邪于外;预防疾病;身心共育,调节情绪。OR功能障碍的发生与子宫相关经络和脏器密切相关。针刺治疗OR功能障碍的机制可能与生殖内分泌激素水平、卵巢组织形态、免疫系统、颗粒细胞凋亡以及相关的信号转导途径有关。针刺治疗OR降低的临床疗效体现在改善月经和排卵;改善OR功能,促进妊娠;改善卵巢局部微环境;改善负面情绪,提高生活质量,从而影响妊娠结局。本文根据近年来的研究结果,总结了针灸治疗OR功能下降的作用机制和临床效果,分析了针灸治疗疾病的优缺点,为针灸在临床上应用于OR功能下降提供了理论依据。
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来源期刊
World Journal of Traditional Chinese Medicine
World Journal of Traditional Chinese Medicine Medicine-Complementary and Alternative Medicine
CiteScore
5.40
自引率
2.30%
发文量
259
审稿时长
24 weeks
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