Epidemiological Burden of Lower Limb Spasticity in Adults: A Systematic Review

Journal of medical research and innovation Pub Date : 2019-11-09 DOI:10.32892/jmri.195

Mamoona Javed, Muhammad Ali

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引用次数: 2

Abstract

Objective: The objective of this study was to investigate the burden of disease associated with lower limb spasticity (LLS) and its complications in adults. Methods: A systematic search of MEDLINE and EMBASE identified 9 studies published between November 2012 and July 2019 that assessed the epidemiological burden associated with LLS. Results: LLS was found to occur in one-third of adults after neuromyelitis optica spectrum disorder (NMOSD), one quarter to one third with multiple sclerosis, one quarter to half with Parkinson’s disease and roughly half with stroke. LLS reduces mobility and diminishes the quality of life. LLS complications, especially injuries following falls are a common occurrence. Conclusion: Given the high prevalence among adults with common disorders, such as stroke; the evidence on the burden of LLS is somewhat finite. Further research is needed to explore the trends over time and across different geographical regions in the incidence and prevalence of LLS. The dearth of high-quality evidence for LLS suggests a lack of awareness of the problem and interest in it, and hence, the unmet need among patients and their carers.

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成人下肢痉挛的流行病学负担:一项系统综述

目的:本研究的目的是调查成人下肢痉挛(LLS)相关的疾病负担及其并发症。方法:系统检索MEDLINE和EMBASE，确定了2012年11月至2019年7月期间发表的9项研究，这些研究评估了与LLS相关的流行病学负担。结果:LLS发生在三分之一的视神经脊髓炎谱系障碍(NMOSD)后，四分之一至三分之一的多发性硬化症患者，四分之一至一半的帕金森病患者和大约一半的中风患者。LLS降低了活动能力，降低了生活质量。LLS并发症，尤其是跌倒后的损伤是常见的。结论:鉴于成人卒中等常见疾病的高患病率;关于LLS负担的证据有些有限。需要进一步的研究来探索LLS的发病率和患病率随时间和不同地理区域的变化趋势。缺乏高质量的LLS证据表明缺乏对这个问题的认识和兴趣，因此，患者及其护理人员的需求未得到满足。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of medical research and innovation

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