Qualitative properties of solutions to a mass-conserving free boundary problem modeling cell polarization

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-08-03 DOI:10.1080/03605302.2023.2247467
Anna Logioti, B. Niethammer, Matthias Röger, J. Velázquez
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Abstract

Abstract We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. We have justified the well-posedness of this problem and have further proved uniqueness of solutions and global stability of steady states. In this paper we investigate qualitative properties of the free boundary. We present necessary and sufficient conditions for the initial data that imply continuity of the support at t = 0. If one of these assumptions fail, then jumps of the support take place. In addition we provide a complete characterization of the jumps for a large class of initial data.
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细胞极化的守恒质量自由边界问题解的定性性质
摘要考虑一个抛物型非局部自由边界问题,该问题已被导出为模拟细胞极化的体-表面反应-扩散系统的极限。我们证明了这个问题的适定性,并进一步证明了解的唯一性和稳态的全局稳定性。本文研究了自由边界的定性性质。给出了初始数据在t = 0时支持连续性的充分必要条件。如果这些假设中的一个不成立,那么就会发生支撑的跳跃。此外,我们还提供了一大类初始数据的跳跃的完整表征。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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