Anna Logioti, B. Niethammer, Matthias Röger, J. Velázquez
{"title":"Qualitative properties of solutions to a mass-conserving free boundary problem modeling cell polarization","authors":"Anna Logioti, B. Niethammer, Matthias Röger, J. Velázquez","doi":"10.1080/03605302.2023.2247467","DOIUrl":null,"url":null,"abstract":"Abstract We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. We have justified the well-posedness of this problem and have further proved uniqueness of solutions and global stability of steady states. In this paper we investigate qualitative properties of the free boundary. We present necessary and sufficient conditions for the initial data that imply continuity of the support at t = 0. If one of these assumptions fail, then jumps of the support take place. In addition we provide a complete characterization of the jumps for a large class of initial data.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1080/03605302.2023.2247467","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. We have justified the well-posedness of this problem and have further proved uniqueness of solutions and global stability of steady states. In this paper we investigate qualitative properties of the free boundary. We present necessary and sufficient conditions for the initial data that imply continuity of the support at t = 0. If one of these assumptions fail, then jumps of the support take place. In addition we provide a complete characterization of the jumps for a large class of initial data.