A Case Series Coexistence of PFO with Other Conditions - Who’s the Culprit?

Dessytha Nathania Hudaja, A. S. Soetjipto, Queen Sugih Ariyani, Michael Soesanto, I. Pardede
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Abstract

Abstract.  Background: Patent foramen ovale (PFO) is a major cause of cryptogenic stroke (CS). However, it is still possible that PFO comes with those other conditions during evaluation. This paper presents a series of CS cases highly suspected due to PFO origin with each of its special presentations. Case illustration/summary of a review article: We present three cases of CS with PFO as a possible contributing factor. Case 1 showed a patient with repeated ischemic strokes that was investigated to be cryptogenic in origin. Case 2 showed CS with PFO and occult atrial fibrillation. Case 3 showed CS at a young age caused by a PFO with protein C/S deficiency. Conclusion: The role of PFO as a culprit, risk factor, or a coincidental finding in CS is still debatable and is a controversial issue. Determining PFO as a cause of CS requires a thorough consideration of clinical and PFO anatomical/morphological factors.
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PFO与其他疾病共存的案例系列——谁是罪魁祸首?
摘要背景:卵圆孔未闭(PFO)是引起隐源性脑卒中(CS)的主要原因。然而,在评估过程中,PFO仍有可能附带其他条件。本文介绍了一系列因PFO起源而高度怀疑的CS病例及其每一种特殊表现。案例说明/综述文章摘要:我们介绍了三例CS,PFO可能是一个促成因素。病例1显示了一名反复缺血性中风的患者,该患者被研究为来源不明。病例2显示CS伴PFO和隐匿性心房颤动。病例3显示年轻时的CS是由蛋白C/S缺乏的PFO引起的。结论:PFO作为CS的罪魁祸首、危险因素或巧合发现的作用仍然存在争议,也是一个有争议的问题。确定PFO是CS的原因需要彻底考虑临床和PFO解剖/形态学因素。
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