A. Abdallah, R. Mohareb, M. H. Helal, Mariam M. Abd Elkader
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引用次数: 0
Abstract
Many new cyclized pyran systems with a potential anti-cancer activity were designed and prepared. Pyran systems showed high reactivity to various chemical reagents. 24 products of the prepared compounds were chosen and tested in (mM) as respectable anticancer factors. The findings revealed that compounds 3b, 6b, and 8 were the widely effective compounds against the three cancer cell lines including A-549 (lung carcinoma), HC-29 (colorectal adenocarcinoma), and MKN-45 (gastric cancer) compared to the standard reference control foretinib.
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