Physical Condition and Risk of Hospitalization and Polypharmacy in Older Adults.

IF 2.2 4区 医学 Q3 GERIATRICS & GERONTOLOGY Rejuvenation research Pub Date : 2022-05-24 DOI:10.1089/rej.2021.0030
Ana Fernández-Araque, Laura García-de-Diego, María Martínez-Ferrán, I. Diez-Vega, T. Yvert, T. Mingo, C. Santiago, H. Pareja-Galeano, Z. Verde
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引用次数: 1

Abstract

Hospitalization in older population leads to a decline in physical function, physical condition and independency. However, a scarce number of studies has addressed the effect of being in good physical condition on the risk of hospitalization and polypharmacy in older people. Therefore, this study aims to examine the relationship between physical condition and other health factors, and the incidence of hospitalization and polypharmacy in Spanish older persons. For this cross-sectional study 102 community-dwelling persons aged 80 years or older who were being treated at three primary care centers. The data collected were number of hospitalizations and medications, dietary habits, nutrition status, quality of life, independence in activities of daily life, physical performance and associated genotype data. Scoring higher in the tests Chair stand and 8-Foot Up-and-go was found associated with reduced risks of hospitalization [OR = .45 (95% CI = .2, .99); OR .32 (95% CI = .12, .86)] and polypharmacy [OR = .36 (95% CI = .16, .8); OR= .28 (95% CI = .1, .78)]. The number of medications was also lower in individuals with a greater aerobic capacity and activities of daily life independence [OR = .28 (95% CI = .1, .78); OR = .37 (95% CI = .16, .82)]. No associations were found with the remaining physical performance tests or other factors assessed. Our findings point to benefits of greater strength, balance and aerobic capacity in terms of reducing the risk of hospitalization and polypharmacy.
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老年人身体状况与住院和多药的风险
老年人住院会导致身体功能、身体状况和独立性下降。然而,很少有研究涉及身体状况良好对老年人住院和多药治疗风险的影响。因此,本研究旨在探讨西班牙老年人的身体状况和其他健康因素之间的关系,以及住院和多药治疗的发生率。在这项横断面研究中,102名80岁或以上的社区居民在三个初级保健中心接受治疗。收集的数据包括住院人数和药物、饮食习惯、营养状况、生活质量、日常活动的独立性、身体表现和相关基因型数据。研究发现,在椅子站立和8英尺上下运动的测试中得分较高与住院风险降低相关[OR=.45(95%CI=0.2,.99);OR.32(95%CI=0.12,.86)]和多药治疗风险降低[OR=.36(95%CI=1.16,.8);OR=0.28(95%CI=1.1,.78)]。有氧能力和日常生活独立性较强的个体的药物数量也较低[OR=.28(95%置信区间=1.78);OR=.37(95%CI=.16,.82)]。未发现与剩余的身体表现测试或其他评估因素有关。我们的研究结果表明,增强力量、平衡和有氧能力有助于降低住院和多药治疗的风险。
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来源期刊
Rejuvenation research
Rejuvenation research 医学-老年医学
CiteScore
4.50
自引率
0.00%
发文量
41
审稿时长
3 months
期刊介绍: Rejuvenation Research publishes cutting-edge, peer-reviewed research on rejuvenation therapies in the laboratory and the clinic. The Journal focuses on key explorations and advances that may ultimately contribute to slowing or reversing the aging process, and covers topics such as cardiovascular aging, DNA damage and repair, cloning, and cell immortalization and senescence. Rejuvenation Research coverage includes: Cell immortalization and senescence Pluripotent stem cells DNA damage/repair Gene targeting, gene therapy, and genomics Growth factors and nutrient supply/sensing Immunosenescence Comparative biology of aging Tissue engineering Late-life pathologies (cardiovascular, neurodegenerative and others) Public policy and social context.
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