Isolation of amygdalin epimer at high diastereomeric purity and its structural characterization by spectroscopic and Q-TOF LC-MS methods

IF 1.8 Q3 CHEMISTRY, ANALYTICAL Journal of Chemical Metrology Pub Date : 2021-08-18 DOI:10.25135/jcm.60.2105.2076
Irfan Capan, S. Servi, A. Aysal, Pshtiwan Raheem Sabır
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引用次数: 1

Abstract

Amygdalin, a cyanogenic glycoside mostly found in the bitter almond kernel, plays an important role in conventional and modern medicine applications. The high diastereomeric purity amygdalin was isolated with chromatographic purification methods and recrystallization. Amygdalin and neoamygdalin were separated chromatographically using the porous graphitic carbon column. Identification and confirmation of each molecule was performed with the ESI Quadrupole Time of Flight system coupled with a reversed phase LC.
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高非对映异构体纯度苦杏仁苷表聚体的分离及其光谱和Q-TOF LC-MS表征
苦杏仁苷是一种主要存在于苦杏仁中的发蓝糖苷,在传统和现代医学中发挥着重要作用。采用色谱纯化和重结晶的方法分离得到高非对映体纯度的苦杏仁苷。采用多孔石墨碳柱色谱分离苦杏仁苷和新苦杏仁苷。每个分子的鉴定和确认是用ESI四极飞行时间系统与反相LC耦合进行的。
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来源期刊
Journal of Chemical Metrology
Journal of Chemical Metrology CHEMISTRY, ANALYTICAL-
CiteScore
2.30
自引率
15.40%
发文量
7
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