Obtaining preparations with increased content of bioactive compounds from eight types of berries

IF 1.5 4区农林科学 Q3 PLANT SCIENCES Journal of Berry Research Pub Date : 2023-09-07 DOI:10.3233/jbr-230020

Natalia Żurek, Agata Pawłowska, I. Kapusta

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引用次数: 0

Abstract

BACKGROUND: Cranberries, black and red currants, strawberries, chokeberries, raspberries, blueberries and blackberries, due to the high content of polyphenolic compounds, become an excellent matrix for the production of preparations that can be used as nutraceuticals. OBJECTIVE: Evaluation of the content of bioactive compounds and health-promoting activity of preparations from polyphenolic fractions isolated from eight types of berries. METHODS: The preparations were obtained by lyophilization of the polyphenolic fraction of fruit extracts, and then they were evaluated in terms of physicochemical properties, content of polyphenolic compounds and antioxidant, antidiabetic, antiobesity and anticancer activity. RESULTS: The analyzes showed a very diverse content of bioactive compounds and a high health-promoting potential significantly depending on the type of fruit. In total, 61 polyphenolic compounds were identified, with anthocyanins being the dominant group. A positive correlation was found between the content of polyphenolic compounds and high antioxidant activity. A cytotoxic effect on colorectal adenocarcinoma cells (Caco-2) was also found. In addition, all the obtained preparations turned out to be effective inhibitors of enzymes promoting diabetes and obesity. CONCLUSIONS: The obtained preparations can be used in the production of nutraceuticals or functional food additives, applicable in the prevention and treatment of lifestyle diseases.

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从8种浆果中获得生物活性化合物含量增加的制剂

背景:蔓越莓、黑醋栗、红醋栗、草莓、蔓越莓、覆盆子、蓝莓和黑莓，由于其多酚类化合物含量高，成为生产营养保健品制剂的优良基质。目的:评价8种浆果多酚提取物的生物活性化合物含量及保健活性。方法:将水果提取物的多酚部分进行冻干制备，并对其理化性质、多酚类化合物含量及抗氧化、抗糖尿病、抗肥胖和抗癌活性进行评价。结果:分析表明，根据水果的类型，其生物活性化合物的含量非常多样化，具有很高的促进健康的潜力。共鉴定出61种多酚类化合物，其中花青素为优势基团。多酚类化合物含量与抗氧化活性呈正相关。对结直肠腺癌细胞(Caco-2)也有细胞毒性作用。此外，所有获得的制剂被证明是促进糖尿病和肥胖的酶的有效抑制剂。结论:所得制剂可用于生产保健品或功能性食品添加剂，适用于生活方式疾病的防治。

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来源期刊

Journal of Berry Research Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

3.50

自引率

11.80%

发文量

期刊介绍： The main objective of the Journal of Berry Research is to improve the knowledge about quality and production of berries to benefit health of the consumers and maintain profitable production using sustainable systems. The objective will be achieved by focusing on four main areas of research and development: From genetics to variety evaluation Nursery production systems and plant quality control Plant physiology, biochemistry and molecular biology, as well as cultural management Health for the consumer: components and factors affecting berries'' nutritional value Specifically, the journal will cover berries (strawberry, raspberry, blackberry, blueberry, cranberry currants, etc.), as well as grapes and small soft fruit in general (e.g., kiwi fruit). It will publish research results covering all areas of plant breeding, including plant genetics, genomics, functional genomics, proteomics and metabolomics, plant physiology, plant pathology and plant development, as well as results dealing with the chemistry and biochemistry of bioactive compounds contained in such fruits and their possible role in human health. Contributions detailing possible pharmacological, medical or therapeutic use or dietary significance will be welcomed in addition to studies regarding biosafety issues of genetically modified plants.