Cirugía y radioembolización de tumores hepáticos

IF 1.6 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2023-07-01 DOI:10.1016/j.remn.2023.06.003
D. Aliseda , F. Rotellar , L. Sancho , J.F. Batidas , A. Martínez de la Cuesta , M. Rodríguez-Fraile
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引用次数: 0

Abstract

Surgical resection is considered the curative treatment par excellence for patients with primary or metastatic liver tumors. However, less than 40% of them are candidates for surgery, either due to non-modifiable factors (comorbidities, age, liver dysfunction...), or to the invasion or proximity of the tumor to the main vascular requirements, the lack of a future liver remnant (FLR) adequate to maintain postoperative liver function, or criteria of tumor size and number. In these last factors, hepatic radioembolization has been shown to play a role as a presurgical tool, either by hypertrophy of the FLR or by reducing tumor size that manages to reduce tumor staging (term known as “downstaging”). To these is added a third factor, which is its ability to apply the test of time, which makes it possible to identify those patients who present progression of the disease in a short period of time (both locally and at distance), avoiding a unnecessary surgery. This paper aims to review RE as a tool to facilitate liver surgery, both through the experience of our center and the available scientific evidence.

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肝脏肿瘤的手术和放射栓塞
手术切除被认为是治疗原发性或转移性肝肿瘤的最佳方法。然而,由于不可改变的因素(合并症、年龄、肝功能障碍等),或肿瘤侵犯或靠近主要血管,缺乏足以维持术后肝功能的未来肝残体(FLR),或肿瘤大小和数量的标准,只有不到40%的患者适合手术治疗。在最后这些因素中,肝放射栓塞已被证明作为一种术前工具发挥作用,要么通过肥厚FLR,要么通过缩小肿瘤大小来减少肿瘤分期(称为“降分期”)。除此之外,还有第三个因素,即它能够应用时间测试,这使得有可能在短时间内(局部和远距离)识别那些出现疾病进展的患者,避免不必要的手术。本文旨在通过本中心的经验和现有的科学证据来回顾RE作为促进肝脏手术的工具。
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来源期刊
Revista Espanola De Medicina Nuclear E Imagen Molecular
Revista Espanola De Medicina Nuclear E Imagen Molecular RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
16.70%
发文量
85
审稿时长
24 days
期刊介绍: The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members. The Journal, which publishes 6 regular issues per year, has the promotion of research and continuing education in all fields of Nuclear Medicine as its main aim. For this, its principal sections are Originals, Clinical Notes, Images of Interest, and Special Collaboration articles.
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