Analysis of Age Distribution of Bone Mineral Density by Dual-Energy X-Ray Absorptiometry

A. Petraikin, Z. R. Artyukova, N. Kudryavtsev, D. Semenov, A. Smorchkova, S. S. Repin, E. Akhmad, F. A. Petriaikin, L. A. Nisovtsova, A. V. Vladzimirskyy
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Abstract

Objective: to conduct the study of age distribution of bone mineral density (BMD) by the database of dualenergy X-ray absorptiometry (DXA) and to compare it with datа of population NHANES study. Material and methods. We used data from the densitometry of three-zone (total hip (TH), femoral neck (FN), and lumbar spine) measured by DXA from two outpatient clinics. The obtained data were compared with NHANES III for TH and FN and with NHANES 2005-08 for lumbar spine. The BMD value was corrected with the calibration coefficient for each DXA scanner. Adjustments were also made for the population distribution by sex and age. Results. Compared with NHANES for FN and TH, the obtained BMD values were significantly decreased for patients aged less than 50 years (men and women). The BMD values for FN and TH were unsignificantly decreased in men older 50 years. In women older 50 years unsignificantly decreased BMD values for FN and a significantly increased BMD values for TH were observed. The BMD values were decreased for lumbar spine in men and women throughout this age interval (more than 50 years old). Conclusion. The population BMD distribution in men and women was assessed by DXA method. The obtained dependence of the BMD for FN in women older 50 years was in good agreement with the results given by Russian and foreign authors.
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双能x线骨密度仪分析骨密度的年龄分布
目的:利用双能x线骨密度仪(DXA)数据库研究骨密度(BMD)的年龄分布,并与人口NHANES研究数据进行比较。材料和方法。我们使用了来自两个门诊诊所的DXA测量的三个区域(全髋关节(TH),股骨颈(FN)和腰椎)的密度测量数据。将获得的数据与NHANES III (TH和FN)和NHANES 2005-08(腰椎)进行比较。用每个DXA扫描仪的校准系数校正BMD值。按性别和年龄划分的人口分布也作了调整。结果。与FN和TH的NHANES相比,年龄小于50岁的患者(男性和女性)获得的BMD值显着降低。在50岁以上的男性中,FN和TH的骨密度值没有明显下降。在50岁以上的女性中,观察到FN骨密度值无显著下降,而TH骨密度值显著增加。在这个年龄段(超过50岁),男性和女性腰椎的骨密度值都有所下降。结论。采用DXA法评估男女人群骨密度分布。所获得的骨密度对50岁以上妇女FN的依赖性与俄罗斯和国外作者给出的结果很好地一致。
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36 weeks
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