Dynamic architecture based deep learning approach for glioblastoma brain tumor survival prediction

Disha Sushant Wankhede, R. Selvarani
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引用次数: 11

Abstract

A correct diagnosis of brain tumours is crucial to making an accurate treatment plan for patients with the disease and allowing them to live a long and healthy life. Among a few clinical imaging modalities, attractive reverberation imaging gives extra different data about the tissues. The use of MRI-Magnetic Resonance Imaging tests is a significant method for identifying disorders throughout the human body. Deep learning provides a solution for efficiently detecting Brain Tumour. The work has used MRI images for predicting the glioblastoma of brain tumours. Initially, data is retrieved from hospitals in form of an image database to continue with the brain tumour prediction. Pre-processing of dataset images is a mandatory step to enhance the accuracy and smooth line supplementary stages. The intensity value of each MRI (Magnetic Resonance Imaging) is subtracted by the mean intensity value and standard deviation of the brain region. Further, reduce the medical image noise by employing a bilateral filter. Further, the preprocessed medical images are used for extracting the radiomics features from images as well as tumour segmentation. Thus the work adopts the tumor is automatically segmented into four compartments using mutually exclusive rules using Modified Fuzzy C Means Clustering (MFCM). The clustering-based approach is very beneficial in MR tumour segmentation; it categorizes the pixels using certain radiomics features. The most important problem in the radiomics-based machine learning model is the dimension of data. Moreover, using a GWO (Grey Wolf Optimizer) with rough set theory, we propose a novel dimensionality reduction algorithm. This method is employed to find the significant features from the extracted images and differentiate HG (high-grade) and LG (Low-grade) from GBM while varying feature correlation limits were applied to remove redundant features. Finally, the article proposed the dynamic architecture of Multilevel Layer modelling in Faster R-CNN (MLL-CNN) approach based on feature weight factor and relative description model to build the selected features. This reduces the overall computation and performs long-tailed classification. This results in the development of CNN training performance more accurate. Results show that the general endurance expectation of GBM cerebrum growth with more prominent exactness of about 95% with the decreased blunder rate to be 2.3%. In the calculation of similarity between segmented tissues and ground truth, different tools produce correspondingly different predictions.

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基于动态架构的深度学习方法用于胶质母细胞瘤脑肿瘤生存预测
脑肿瘤的正确诊断对于为患者制定准确的治疗计划,让他们过上健康长寿的生活至关重要。在几种临床成像方式中,吸引混响成像提供了关于组织的额外不同数据。使用核磁共振成像测试是识别整个人体疾病的重要方法。深度学习为脑肿瘤的有效检测提供了解决方案。这项工作已经使用核磁共振成像来预测脑肿瘤的胶质母细胞瘤。最初,数据以图像数据库的形式从医院检索,以继续进行脑肿瘤预测。数据集图像的预处理是提高数据集精度和线条补充阶段平滑化的必要步骤。每个MRI(磁共振成像)的强度值减去大脑区域的平均强度值和标准差。进一步,通过采用双边滤波器降低医学图像噪声。此外,将预处理后的医学图像用于提取图像中的放射组学特征以及肿瘤分割。因此,采用改进模糊C均值聚类(MFCM),采用互斥规则将肿瘤自动分割为四个区室。基于聚类的方法在MR肿瘤分割中非常有用;它使用特定的放射组学特征对像素进行分类。在基于放射学的机器学习模型中,最重要的问题是数据的维度。此外,我们利用粗糙集理论中的灰狼优化器(GWO),提出了一种新的降维算法。该方法从提取的图像中寻找显著特征,并将HG (high-grade)和LG (Low-grade)与GBM区分开来,同时采用不同的特征相关限去除冗余特征。最后,本文提出了基于特征权重因子和相对描述模型构建所选特征的Faster R-CNN (MLL-CNN)方法中多层建模的动态架构。这减少了总体计算并执行长尾分类。这使得CNN训练性能的发展更加准确。结果表明,GBM脑生长的一般耐力预期准确率较突出,达到95%左右,误差率下降2.3%。在计算分割组织与ground truth之间的相似性时,不同的工具会产生相应不同的预测结果。
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来源期刊
Neuroscience informatics
Neuroscience informatics Surgery, Radiology and Imaging, Information Systems, Neurology, Artificial Intelligence, Computer Science Applications, Signal Processing, Critical Care and Intensive Care Medicine, Health Informatics, Clinical Neurology, Pathology and Medical Technology
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