Recorded Diagnosis of Gender Identity Disorder Is Strongly Associated with Suicide Mortality.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI:10.1089/trgh.2022.0110
Geoffrey D Kahn, Elizabeth Lockhart, Gregory E Simon, Ashli A Owen-Smith, Rebecca C Rossom, Arne L Beck, Frances L Lynch, Yihe G Daida, Christine Y Lu, Stephen Waring, Hsueh-Han Yeh, Brian K Ahmedani
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Abstract

We assessed the association between gender identity disorder (GID) diagnosis and suicide in a retrospective case-control study (N=300,364) from nine health care systems between 2000 and 2015. Adjusting for age and sex, the odds ratio for GID was 18.6 (95% confidence interval 7.0-49.5). Adjusting additionally for comorbid psychiatric diagnoses, the odds ratio was 4.75 (1.78-12.68), higher than depressive (3.96, 3.64-4.31), alcohol use (3.42, 3.04-3.84), bipolar (2.42, 2.10-2.80), and psychotic disorders (1.44, 1.22-1.70). These U.S. data support prior research demonstrating increased suicide risk among patients with diagnosed GID, who may benefit from targeted screening and intervention within health care systems.

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性别认同障碍的记录诊断与自杀死亡率密切相关
我们在一项回顾性病例对照研究中评估了性别认同障碍(GID)诊断与自杀之间的关系(N=300,364),该研究来自 2000 年至 2015 年间的九个医疗保健系统。对年龄和性别进行调整后,GID 的几率比为 18.6(95% 置信区间为 7.0-49.5)。再根据合并精神病诊断进行调整后,几率比为 4.75(1.78-12.68),高于抑郁症(3.96,3.64-4.31)、饮酒(3.42,3.04-3.84)、双相情感障碍(2.42,2.10-2.80)和精神病性障碍(1.44,1.22-1.70)。这些美国数据支持了之前的研究,这些研究表明,确诊的 GID 患者自杀风险增加,医疗保健系统可能会对他们进行有针对性的筛查和干预。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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