Ekin Guney , Kwun Wah Wen , Roberto Ruiz-Cordero , Linda Ferrell , Ryan M. Gill , Dennis O'Malley , Kirk D. Jones , Robert Ohgami
{"title":"A solid variant of splenic mesothelial cyst, a case report with molecular analysis","authors":"Ekin Guney , Kwun Wah Wen , Roberto Ruiz-Cordero , Linda Ferrell , Ryan M. Gill , Dennis O'Malley , Kirk D. Jones , Robert Ohgami","doi":"10.1016/j.ehpc.2021.200509","DOIUrl":null,"url":null,"abstract":"<div><p>Cystic lesions of the spleen are rare and challenging to diagnose, often generating a broad differential diagnosis. However, a comprehensive approach which includes molecular studies, may result in an accurate diagnosis and further provide insight into underlying etiologies. In this study, we report an extensive analysis of a rare solid variant of splenic mesothelial cyst by utilizing clinical, imaging, gross, histopathologic, immunohistochemical and molecular findings.</p></div>","PeriodicalId":38075,"journal":{"name":"Human Pathology: Case Reports","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ehpc.2021.200509","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Pathology: Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214330021000389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 2
Abstract
Cystic lesions of the spleen are rare and challenging to diagnose, often generating a broad differential diagnosis. However, a comprehensive approach which includes molecular studies, may result in an accurate diagnosis and further provide insight into underlying etiologies. In this study, we report an extensive analysis of a rare solid variant of splenic mesothelial cyst by utilizing clinical, imaging, gross, histopathologic, immunohistochemical and molecular findings.