Spinal dystonia and other spinal movement disorders

Dystonia Pub Date : 2023-08-16 DOI:10.3389/dyst.2023.11303
Shlok Sarin, Temitope Lawal, H. Abboud
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Abstract

While traditionally considered a disorder of the basal ganglia, brainstem, and cerebellum, multiple reports have shown that spinal cord pathologies may lead to dystonia. In this article, we first discuss various spinal movement disorders and the differences between tonic spasms, spinal dystonia, spinal myoclonus, spinal tremors, and paroxysmal dyskinesia. We review potential pathogenesis of spinal dystonia. We then focus on reports of dystonia secondary to spinal cord demyelinating diseases such as multiple sclerosis and neuromyelitis optica spectrum disorders. We conclude by discussing the potential treatment options for spinal dystonia.
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脊柱肌张力障碍和其他脊柱运动障碍
虽然传统上认为这是一种基底神经节、脑干和小脑的疾病,但多项报告显示脊髓病变可能导致肌张力障碍。在这篇文章中,我们首先讨论各种脊柱运动障碍以及强直性痉挛、脊柱肌张力障碍、脊柱肌阵挛、脊柱震颤和阵发性运动障碍之间的区别。我们回顾脊髓肌张力障碍的潜在发病机制。然后,我们重点报道继发于脊髓脱髓鞘疾病的肌张力障碍,如多发性硬化症和视神经脊髓炎谱系障碍。我们最后讨论脊柱肌张力障碍的潜在治疗方案。
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