A study of changes in Mean Ocular Perfusion Pressure and Intra-Ocular Pressure among patients undergoing hemodialysis

Abstract

Abstract Background:During hemodialysis there is decrease in both systolic blood pressure (SBP) and diastolic blood pressure (DBP) and hence Mean Arterial Pressure (MAP) due to decrease in body fluid volume. Due to reduction in MAP there is decrease in Mean Ocular Perfusion Pressure (MOPP) and also there is increase in IOP during dialysis. Objective:To study changes in MOPP and IOP among patients undergoing hemodialysis Methods:An observational study was carried out among 100 patients undergoing hemodialysis Under aseptic condition, Proparacaine eye drops were instilled in both eyes, IOP was measured by Schiotz Indentation Tonometer 30 min before, during hemodialysis and 30 min after hemodialysis in supine position. Tonometer was sterilized by Isopropyl alcohol and was washed with normal saline before using on next patient. Systolic and diastolic blood pressure were measured by using sphygmomanometer 30 min before, during and 30 min after hemodialysis. Results:The variations in the SBP, DBP and MAP before, during and after hemodialysis were not statistically significant (p>0.05). There was significant differences for IOP between before, during and after hemodialysis and same for MOPP except before and 30 min after hemodialysis (p < 0.0001). Conclusion:Significant fluctuations were seen from the present study in the intra-ocular pressure and mean ocular perfusion pressure during, before and after hemodialysis.