Comparison of the Patients Suffering from Relapsing-Remitting Multiple Sclerosis with Healthy Individuals regarding Serum Selenium and Zinc Levels

Q4 Medicine pzshkhy blyny bn syn Pub Date : 2020-12-01 DOI:10.29252/AJCM.27.3.157
A. Vahidinia, M. Mazdeh, Salahadin Adman, Z. Cheraghi
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Abstract

Background and Objective: Multiple sclerosis is an autoimmune disease of the central nervous system that causes demyelination and axonal damage. There are contradictory results regarding the effects of zinc and selenium on the prevention or reduction of multiple sclerosis symptoms. This study aimed to compare selenium and serum zinc levels of the patients suffering from relapsing-remitting multiple sclerosis with those of healthy individuals. Materials and Methods: This case-control study compared 30 patients suffering from relapsing-remitting multiple sclerosis (case) with 30 healthy individuals (control) regarding serum zinc and selenium levels. The cases and controls were matched in terms of age, gender, and smoking history using frequency matching methods. The data were analyzed using STATA software (version 15). A p-value less than 0.05 was considered statistically
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复发性缓解性多发性硬化患者和健康人血清硒锌水平的比较
背景与目的:多发性硬化症是一种中枢神经系统自身免疫性疾病,可导致脱髓鞘和轴突损伤。关于锌和硒在预防或减轻多发性硬化症症状方面的作用,有相互矛盾的结果。本研究旨在比较复发缓解型多发性硬化症患者与健康人的血清硒和锌水平。材料与方法:本病例对照研究比较了30例复发-缓解型多发性硬化症患者(病例)和30例健康人(对照组)的血清锌和硒水平。使用频率匹配方法将病例和对照组在年龄、性别和吸烟史方面进行匹配。使用STATA软件(版本15)分析数据。p值小于0.05被认为具有统计学意义
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
16
审稿时长
8 weeks
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