Injectable hydrogels for anti‐tumour treatment: a review

IF 1.6 Q4 ENGINEERING, BIOMEDICAL Biosurface and Biotribology Pub Date : 2020-09-22 DOI:10.1049/bsbt.2020.0020
Huang He, Chaoming Xie, Xiong Lu
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引用次数: 6

Abstract

Injectable hydrogels have become the material of choice for the treatment of solid tumours based on their advantages in loading anti-tumour materials. This study reviews the main scientific research achievements on anti-tumour injectable hydrogels in recent years. The gel-forming mechanism of anti-tumour injectable hydrogels was listed, and the advantages and difficulties of each gel-forming mechanism were summarised. In addition, several current anti-tumour methods based on injectable hydrogels were discussed, including chemotherapy, hyperthermia-based therapy, catalytic therapy and immune therapy, as well as the integration of diagnosis and treatment to monitor the progress of cancer treatment. The anti-tumour mechanism and the advantages and disadvantages of various tumour treatments were analysed. Finally, the future development trend of injectable hydrogels for anti-tumour therapy was discussed.
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用于抗肿瘤治疗的可注射水凝胶:综述
可注射水凝胶由于其装载抗肿瘤物质的优点,已成为治疗实体肿瘤的首选材料。本文综述了近年来抗肿瘤注射水凝胶的主要科研成果。列举了抗肿瘤注射水凝胶的成胶机理,总结了各种成胶机理的优点和难点。此外,还讨论了目前基于可注射水凝胶的几种抗肿瘤方法,包括化疗、热疗、催化治疗和免疫治疗,以及诊断和治疗的一体化,以监测癌症治疗的进展。分析了抗肿瘤机制及各种肿瘤治疗方法的优缺点。最后,对今后抗肿瘤注射用水凝胶的发展趋势进行了展望。
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来源期刊
Biosurface and Biotribology
Biosurface and Biotribology Engineering-Mechanical Engineering
CiteScore
1.70
自引率
0.00%
发文量
27
审稿时长
11 weeks
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