Management of patients with transcatheter implantable aortic valve

E. Luneva, E. Malev
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Abstract

Valvular heart disease remains one of the causes of cardiovascular morbidity and mortality worldwide. Aortic stenosis is the most common valvular pathology requiring cardiac surgery. For elderly and senile patients with high risks of volumetric cardiac surgery, a new type of biological prosthesis, a transcatheter implantable aortic valve, has become a solution to the problem. Over the past decade catheter interventions for severe valvular heart disease have evolved from balloon dilatation of native stenotic valves to replacement and reconstructive intervention of diseased valves. Transcatheter aortic valve implantation, which is widespread in the USA and Europe, has also begun to be performed in our country, primarily in comorbid groups of patients. Rapid technological advances in device design are likely to improve immediate and long-term outcomes of surgery and expand the current indications for transcatheter aortic valve implantation. The article analyzes the indications for the procedure in accordance with the latest recommendations of 2021, possible complications of the transcatheter aortic valve implantation, as well as the principles of patient management after the procedure, including the principles of drug therapy in this group of patients. Separately, the topic of aortic regurgitation and the possibility of transcatheter aortic valve implantation are touched upon, since this pathology is a new indication that has appeared only in the latest recommendations of the European Society of Cardiology. In this review, we want to acquaint physicians with the indications for transcatheter aortic valve implantation, the main complications, and the principles of managing patients in the perioperative period. The complication rate after transcatheter aortic valve implantation is decreasing due to technical advances and experience of interventional surgeons. In-depth knowledge of potential complications and their prevention plays a key role in improving the immediate and long-term results of surgery.
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经导管植入性主动脉瓣患者的处理
瓣膜性心脏病仍然是世界范围内心血管疾病发病率和死亡率的原因之一。主动脉瓣狭窄是最常见的瓣膜病变,需要进行心脏手术。对于大容量心脏手术高危的老年人和老年患者,一种新型的生物假体——经导管植入式主动脉瓣已经成为解决这一问题的方法。在过去的十年中,导管介入治疗严重瓣膜性心脏病已经从球囊扩张原生狭窄瓣膜发展到病变瓣膜的置换和重建干预。经导管主动脉瓣植入术在美国和欧洲很普遍,在我国也开始进行,主要是在合并症患者中进行。设备设计的快速技术进步可能会改善手术的即时和长期效果,并扩大目前经导管主动脉瓣植入术的适应症。本文根据2021年最新推荐,分析手术适应证,经导管主动脉瓣植入术可能出现的并发症,以及术后患者管理原则,包括该组患者的药物治疗原则。另外,我们还讨论了主动脉瓣反流和经导管主动脉瓣植入术的可能性,因为这种病理是一种新的适应症,仅在欧洲心脏病学会的最新推荐中才出现。在这篇综述中,我们想让医生了解经导管主动脉瓣植入术的适应症、主要并发症以及围手术期患者的处理原则。由于技术的进步和介入外科医生的经验,经导管主动脉瓣植入术的并发症发生率正在下降。深入了解潜在的并发症及其预防在改善手术的即时和长期效果方面起着关键作用。
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