Anti-N-methyl-D-aspartate receptor encephalitis in a 17-year-old girl – a case report

Cezary Witczak, P. Kemnitz, I. Pieczonka-Ruszkowska, A. Mania, Katarzyna Mazur-Melewska, M. Figlerowicz
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Abstract

Autoimmune encephalitis is rare in children and develops as a manifestation of a parainfectious or paraneoplastic syndrome. The disease is characterised by a sudden or subacute onset and a broad spectrum of neurological and/or psychiatric disorders. We present a case of a 17-year-old girl with anti-N-methyl-D-aspartate receptor encephalitis. The patient was admitted to hospital in a severe condition, unconscious, with injuries indicating a recent status epilepticus. Previous infection was found to be the most likely causative factor. Antiviral, antibacterial, immunosuppressive and anticonvulsant treatments were used with good outcomes. The aim of the paper is to point out the need to include autoimmune processes in the differential diagnosis of neuroinfections in children, which will allow for prompt implementation of appropriate treatment and improve prognosis.
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17岁女童抗n -甲基- d -天冬氨酸受体脑炎1例报告
自身免疫性脑炎在儿童中很罕见,是一种副感染或副肿瘤综合征的表现。该疾病的特点是突然或亚急性发作,并伴有广泛的神经和/或精神疾病。我们报告一例17岁女孩的抗N-甲基-D-天冬氨酸受体脑炎。患者入院时情况严重,昏迷,受伤表明近期癫痫持续状态。先前的感染被发现是最有可能的致病因素。抗病毒、抗菌、免疫抑制和抗惊厥治疗效果良好。这篇论文的目的是指出有必要将自身免疫过程纳入儿童神经感染的鉴别诊断中,这将有助于及时实施适当的治疗并改善预后。
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
33
审稿时长
20 weeks
期刊介绍: PEDIATRIA I MEDYCYNA RODZINNA is a peer-reviewed scientific journal publishing original articles that constitute significant contributions to the advancements of paediatrics and family medicine. In addition, PEDIATRIA I MEDYCYNA RODZINNA, publishes information from the medical associations, reports and materials from international congresses, letters to the Editor, information on new medical products as well as abstracts and discussions on papers published in other scientific journals, reviews of books and other publications.
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