Features of the bioelectrical activity of the brain and cerebral hemodynamics in patients with hypertensive dyscirculatory encephalopathy and hypothyroidism

O. Kovalenko, O. V. Litvin
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Abstract

Encephalopathy is common in people of working age. In the last decade there was an important question the relationship of thyroid and cerebrovascular disease. The aim of the study was to investigate the characteristics of the brain’s elektorogenezis and cerebral hemodynamics in patients with hypertensive encephalopathy and related dyscirculatory hypothyroidism. We examined 97 patients, including 60 people with the HDE and the associated hypothyroidism and 37 - with the HDE without hypothyroidism. The fact, that bioelectrical activity of the brain in patients with hypothyroidism and related HDE was mostly characterized by desynchronization and disorganization of the cortical rhythm, was revealed during the study. Changes revealed by the EEG reflected the presence of metabolic and hemodynamic disturbances of the brain. Also, in patients with GDE and accompanying hypothyroidism, according to the duplex scanning of cerebral vessels, there is a significant decrease in cerebral blood supply and structural changes in vessels with a decrease in the elasticity of the common carotid artery and vertebral arteries and a decrease in cerebral reactivity accordingly. Thus, the comorbidity of HDE and hypothyroidism appears credible changes in the functional activity of the brain and decrease in cerebral reactivity.
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高血压性脑病伴甲状腺功能减退患者脑生物电活动及脑血流动力学特征
脑病在劳动年龄人群中很常见。近十年来,甲状腺与脑血管疾病的关系一直是一个重要的问题。本研究旨在探讨高血压脑病伴甲状腺功能减退患者脑电原性和脑血流动力学的特点。我们检查了97例患者,其中60例HDE伴甲状腺功能减退,37例HDE伴甲状腺功能减退。研究发现,甲状腺功能减退和相关HDE患者的脑生物电活动主要以皮质节律的不同步和紊乱为特征。脑电图显示的变化反映了大脑代谢和血流动力学紊乱的存在。同时,GDE合并甲状腺功能减退的患者,脑血管双相扫描显示,脑血供明显减少,血管结构改变,颈总动脉和椎动脉弹性降低,脑反应性相应降低。因此,HDE和甲状腺功能减退的合并症表现为大脑功能活动的可信变化和大脑反应性降低。
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CiteScore
0.10
自引率
0.00%
发文量
34
审稿时长
12 weeks
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