{"title":"New Coronavirus (2019-nCoV): An Insight Toward Preventive Actions and Natural Medicine","authors":"L. Khedmat","doi":"10.34172/ijtmgh.2020.07","DOIUrl":null,"url":null,"abstract":"Today, one of the most critical health issues is the wide outbreak of novel coronavirus infection, which is so far affected 115 countries and territories all around the world. Presenting the possible risks and appropriate health preventive measures, as well as finding some bio-pharma strategies may open a bright horizon to alleviate the number of patients and the rate of disease transmission until discovering the vaccines and definitive treatments. In December 2019, novel coronavirus was initially recognized in Wuhan State, Hubei Province, China. This virus and its disease were called “SARS-CoV-2” and “coronavirus disease 2019 or COVID-19”, respectively. The COVID-19 was quickly spread in other Far East Asian countries and then to the Middle East and Europe.1 Similar to severe acute respiratory syndrome (SARS; 2002-2003) and the Middle East respiratory syndrome (MERS; 2012-ongoing), SARS-CoV-2 is the beta-coronavirus that originated from bats, causing fever, dry cough, and severe acute respiratory (SAR, e.g., breath shortness).2 Other common symptoms of this viral disease are fatigue, sputum production, myalgia or arthralgia, sore throat, headache, chills, nausea or vomiting, nasal congestion, diarrhea, and hemoptysis, and conjunctival congestion.2,3 In general, undesirable clinical outcomes are correlated to older adults and travelers with underlying health issues. Although the clinical diagnosis of COVID-19 in people can be resulted according to their signs, exposures, and chest imaging, nucleic acid testing of respiratory tract samples (eg, throat swabs) can be considered as a “gold standard” to confirm the viral infection.4,5 The COVID-19 outbreak not only can occur under the individual’s close contact with people carrying this virus but also being in areas where ongoing community spread of the virus. Due to the relatively high prevalence rate, many continuing efforts have been made to design guidelines to reduce outbreaks and encourage accurate and timely clinical reporting. From an epidemiologic viewpoint, the assessment of transmission modes, reproduction interval, and clinical spectrum of COVID-19 may have a vital role to prevent or control, and stop its incidence in communities. In this short time, no vaccine or efficient clinical treatment to fight COVID-19 infection has been yet explored. Therefore, the implementation of some preventive health measures as well as experiences of using medicinal herbs with excellent antiviral activities in controlling primary complications in patients will be important. The first step to prevent the spread of COVID-19 is the reduction or abolition of social gathering in areas with an elevated risk of exposure to the virus. A priority to reduce the disease rate is the quarantine of healthy individuals without symptoms at home, while suspected COVID-19 patients should be under quarantine at the assigned hospital and healthcare centers. The next step is the compliance of elementary cleanliness strategies based on the World Health Organization (WHO) recommendations,3 including frequent washing hands for 20 second or more with soapy water, avoiding touching the mouth, nose or eyes, carrying the hand sanitizers, spraying the contact surfaces with 70% isopropyl alcohol, and wearing protective medical masks and gloves for effective self-care needs. Since COVID-19 like other beta-coronaviruses can be spread by increasing the nutrient deficiencies, improving the immune system through vitamin and mineral supplements can act as a defense barrier against the COVID-19 invasion. Ascorbic acid can be the first player in maintaining immunity, although there is no evidence to prevent COVID-19 by receiving this vitamin at mega doses. It was also demonstrated that increasing the intracellular Zn2+ dose could capably http://ijtmgh.com Int J Travel Med Glob Health. 2020 Mar;8(1):44-45 doi 10.34172/ijtmgh.2020.07 TMGH IInternational Journal of Travel Medicine and Global Health J","PeriodicalId":32539,"journal":{"name":"International Journal of Travel Medicine and Global Health","volume":"8 1","pages":"44-45"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Travel Medicine and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/ijtmgh.2020.07","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
Abstract
Today, one of the most critical health issues is the wide outbreak of novel coronavirus infection, which is so far affected 115 countries and territories all around the world. Presenting the possible risks and appropriate health preventive measures, as well as finding some bio-pharma strategies may open a bright horizon to alleviate the number of patients and the rate of disease transmission until discovering the vaccines and definitive treatments. In December 2019, novel coronavirus was initially recognized in Wuhan State, Hubei Province, China. This virus and its disease were called “SARS-CoV-2” and “coronavirus disease 2019 or COVID-19”, respectively. The COVID-19 was quickly spread in other Far East Asian countries and then to the Middle East and Europe.1 Similar to severe acute respiratory syndrome (SARS; 2002-2003) and the Middle East respiratory syndrome (MERS; 2012-ongoing), SARS-CoV-2 is the beta-coronavirus that originated from bats, causing fever, dry cough, and severe acute respiratory (SAR, e.g., breath shortness).2 Other common symptoms of this viral disease are fatigue, sputum production, myalgia or arthralgia, sore throat, headache, chills, nausea or vomiting, nasal congestion, diarrhea, and hemoptysis, and conjunctival congestion.2,3 In general, undesirable clinical outcomes are correlated to older adults and travelers with underlying health issues. Although the clinical diagnosis of COVID-19 in people can be resulted according to their signs, exposures, and chest imaging, nucleic acid testing of respiratory tract samples (eg, throat swabs) can be considered as a “gold standard” to confirm the viral infection.4,5 The COVID-19 outbreak not only can occur under the individual’s close contact with people carrying this virus but also being in areas where ongoing community spread of the virus. Due to the relatively high prevalence rate, many continuing efforts have been made to design guidelines to reduce outbreaks and encourage accurate and timely clinical reporting. From an epidemiologic viewpoint, the assessment of transmission modes, reproduction interval, and clinical spectrum of COVID-19 may have a vital role to prevent or control, and stop its incidence in communities. In this short time, no vaccine or efficient clinical treatment to fight COVID-19 infection has been yet explored. Therefore, the implementation of some preventive health measures as well as experiences of using medicinal herbs with excellent antiviral activities in controlling primary complications in patients will be important. The first step to prevent the spread of COVID-19 is the reduction or abolition of social gathering in areas with an elevated risk of exposure to the virus. A priority to reduce the disease rate is the quarantine of healthy individuals without symptoms at home, while suspected COVID-19 patients should be under quarantine at the assigned hospital and healthcare centers. The next step is the compliance of elementary cleanliness strategies based on the World Health Organization (WHO) recommendations,3 including frequent washing hands for 20 second or more with soapy water, avoiding touching the mouth, nose or eyes, carrying the hand sanitizers, spraying the contact surfaces with 70% isopropyl alcohol, and wearing protective medical masks and gloves for effective self-care needs. Since COVID-19 like other beta-coronaviruses can be spread by increasing the nutrient deficiencies, improving the immune system through vitamin and mineral supplements can act as a defense barrier against the COVID-19 invasion. Ascorbic acid can be the first player in maintaining immunity, although there is no evidence to prevent COVID-19 by receiving this vitamin at mega doses. It was also demonstrated that increasing the intracellular Zn2+ dose could capably http://ijtmgh.com Int J Travel Med Glob Health. 2020 Mar;8(1):44-45 doi 10.34172/ijtmgh.2020.07 TMGH IInternational Journal of Travel Medicine and Global Health J