The Variable Immune Response to SARS-CoV-2 Infection and Potential Treatment with Combination IL-15 and IL-21

Abstract

SARS-Cov-2 is the virus that causes the disease COVID-19. The disease has led to the worst worldwide health crisis in 100 years. While many patients remain asymptomatic, most patients develop a mild respiratory infection. Symptoms include cough, fever and chills, fatigue and body aches, headache and loss of the sense of taste or smell. However, a proportion of patients develop severe disease. Symptoms of severe disease include higher fever, hypoxia and respiratory distress, leading to hospitalization, and sometimes the need for mechanical ventilation and ultimately death [1].