Evaluation of the hemoglobin level in gingival crevice fluid and clinical periodontal parameters in patients with chronic periodontitis

Abstract

Objectives: The present study aimed to evaluate the level of hemoglobin in gingival crevicular fluid (GCF) and its relationship with clinical periodontal parameters in chronic periodontitis.Methods: This cross-sectional study was conducted in patients with chronic periodontitis. Gingival crevicular fluid was sampled and clinical periodontal parameters PI, PPD, CAL, and BOP were measured. The level of hemoglobin in GCF was measured using a hemoglobin kit. Data were analyzed using Spearman's correlation test and Mann-Whitney's test in Stata 14.1 software. Results: 315 teeth from patients with chronic periodontitis were evaluated. There was a strong and direct correlation between the amount of GCF hemoglobin and the amount of PPD, CAL and PI, their correlation coefficient was equal to 0.78, 0.88 and 0.82, respectively (P<0.001). The mean hemoglobin GCF in the positive BOP group was 68.84 ± 30.89 and in the negative BOP group was 59.28 ± 8.03, which showed a significant difference in the average hemoglobin between the two groups (P<0.001). Conclusion: According to the findings of this study, there is a strong correlation between periodontal clinical parameters and the level of GCF hemoglobin, and measuring the level of hemoglobin in the gingival crevice fluid can be an accurate measure and a non-invasive method for investigating periodontal conditions.