Firlianty Firlianty, C. Anwar, A. Najamuddin, S. B. Pratasik
{"title":"Characteristics of Gel Emulsion Formulation of Snakehead (Channa Micropeltes) As Wound Healer","authors":"Firlianty Firlianty, C. Anwar, A. Najamuddin, S. B. Pratasik","doi":"10.20884/1.OA.2018.14.2.545","DOIUrl":null,"url":null,"abstract":"This study is aimed to know the characteristics and the effectivity of gel emulsion of snakehead (Channa micropeltes) extract in accelerating wound healing process. It used experimental method with Complete Randomized Design. Four treatments with 3 replications were employed, i.e. 1%, 2%, and 4% gel emulsion of snakehead Channa micropeltes extract and a control treatment. Results showed that C. micropeltes extract formulated in gel emulsion had white colour, typical aroma of gel emulsion, soft texture with mean dispersion ability of 3 cm, and pH 6. In vivo test on male mices that gel emulsion of C. micropeltes extract was highly effective (P≤0.05) to accelerate wound healing, in which the treatment of 1% gel emulsion gave the highest effect with 98.5% wound healing at day-14, followed with that of control treatment, 95% healing, then 2%, 90% healing and 4%, 90% healing, respectively. Snakehead (Channa micrpeltes) extract formulated in gel emulsion can speed up the wound healing process.","PeriodicalId":31102,"journal":{"name":"OmniAkuatika","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"OmniAkuatika","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20884/1.OA.2018.14.2.545","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This study is aimed to know the characteristics and the effectivity of gel emulsion of snakehead (Channa micropeltes) extract in accelerating wound healing process. It used experimental method with Complete Randomized Design. Four treatments with 3 replications were employed, i.e. 1%, 2%, and 4% gel emulsion of snakehead Channa micropeltes extract and a control treatment. Results showed that C. micropeltes extract formulated in gel emulsion had white colour, typical aroma of gel emulsion, soft texture with mean dispersion ability of 3 cm, and pH 6. In vivo test on male mices that gel emulsion of C. micropeltes extract was highly effective (P≤0.05) to accelerate wound healing, in which the treatment of 1% gel emulsion gave the highest effect with 98.5% wound healing at day-14, followed with that of control treatment, 95% healing, then 2%, 90% healing and 4%, 90% healing, respectively. Snakehead (Channa micrpeltes) extract formulated in gel emulsion can speed up the wound healing process.
本研究旨在了解蛇头提取物凝胶乳的特性及其对伤口愈合的促进作用。采用完全随机设计的实验方法。试验采用1%、2%、4%鱼头微球提取物凝胶乳和对照处理，共4个处理，共3个重复。结果表明，凝胶乳液制得的小檗提取物颜色为白色，具有典型的凝胶乳液香气，质地柔软，平均分散能力为3 cm, pH值为6。在雄性小鼠体内试验表明，微球草提取物凝胶乳对伤口愈合有极好的促进作用(P≤0.05)，其中1%凝胶乳处理效果最好，第14天创面愈合98.5%，其次是对照处理，愈合95%，然后分别为2%、90%和4%、90%。以凝胶乳液形式配制的蛇头精华，可加速伤口愈合。
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