The effect of age on skin elasticity and setup error in optical surface image-guided radiotherapy

Yang He, Jinyan Lei, H. Peng, Huanli Luo, K. Mao, Dengyan Wang, Lifeng Peng, Yiyu Zhu, Qinghong Min, Xuechun Wang, Huan Tang, Qian Xiao, Ying Wang
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Abstract

Objective To investigate the correlation between skin elasticity and setup error in optical surface image-guided radiotherapy. Methods The skin elasticity (R7) data of the head, chest and abdomen were extracted and analyzed its correlation with age by systematic literature review. Fifty-four patients diagnosed with nasopharyngeal carcinoma, breast cancer and cervical cancer were recruited in this study. Firstly, the patients were positioned based on the room laser and markers. Subsequently, the patient position was verified by the Varian On-Board Imager, and then C-Rad Catalyst was adopted to obtain surface images in two states (mask or non-mask) as reference images. In the subsequent fraction treatment, after initial positioning, the local calibration was performed by Catalyst, and setup errors in three directions were recorded. Meanwhile, the patient setup was verified by CBCT twice a week. The Pearson correlation analysis was performed to analyze the correlation between setup error and age. Results The skin elasticity was negatively correlated with aging (P SI>AP. Conclusion In optical surface-guided radiotherapy of head and neck cancer, skin elasticity may be a significant index for assessing the setup errors in male patients. Key words: Skin elasticity; Surface image-guided radiotherapy; Set-up error
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年龄对光学表面图像引导放射治疗中皮肤弹性和设置误差的影响
目的探讨光学表面图像引导放射治疗中皮肤弹性与设置误差的相关性。方法提取头部、胸部和腹部的皮肤弹性(R7)数据,并通过系统的文献回顾分析其与年龄的相关性。本研究招募了50例诊断为鼻咽癌、癌症和癌症的患者。首先,根据房间激光和标记对患者进行定位。随后,通过Varian车载成像仪验证患者位置,然后采用C-Rad Catalyst获得两种状态(掩模或非掩模)的表面图像作为参考图像。在随后的馏分处理中,在初始定位后,通过Catalyst进行局部校准,并记录三个方向上的设置误差。同时,CBCT每周两次对患者设置进行验证。Pearson相关分析用于分析设置误差与年龄之间的相关性。结果皮肤弹性与年龄呈负相关(P SI>AP)。结论在癌症光学表面引导放疗中,皮肤弹性可能是评估男性患者设置误差的重要指标。关键词:皮肤弹性;表面图像引导放疗;设置误差
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期刊介绍: The Chinese Journal of Radiation Oncology is a national academic journal sponsored by the Chinese Medical Association. It was founded in 1992 and the title was written by Chen Minzhang, the former Minister of Health. Its predecessor was the Chinese Journal of Radiation Oncology, which was founded in 1987. The journal is an authoritative journal in the field of radiation oncology in my country. It focuses on clinical tumor radiotherapy, tumor radiation physics, tumor radiation biology, and thermal therapy. Its main readers are middle and senior clinical doctors and scientific researchers. It is now a monthly journal with a large 16-page format and 80 pages of text. For many years, it has adhered to the principle of combining theory with practice and combining improvement with popularization. It now has columns such as monographs, head and neck tumors (monographs), chest tumors (monographs), abdominal tumors (monographs), physics, technology, biology (monographs), reviews, and investigations and research.
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