Go Human! Circadian translational medicine has come of age

Abstract

Circadian rhythms are oscillating biological processes with a rough 24‐hour period and ubiquitously exist in most organisms living on the surface of the earth. These rhythms are manifest of the cycling transcriptome which is driven by the endogenous circadian clock. Given the clock orchestrates half of protein‐ coding genes and most physiologies in humans, it is no exaggeration to say: we are what our clock ticks. Therefore, human health lies in a harmonic relationship between our body clocks and the environment. Despite a great advancement in the molecular mechanism of the circadian clock in the last few decades, investigations on the circadian clock in human health have just emerged [1].