Detecting Suspected Epidemic Cases Using Trajectory Big Data

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2020-04-01 DOI:10.4208/CSIAM-AM.2020-0006
Chuansai Zhou, Wen Yuan, Jun Wang, Hai-feng Xu, Yong Jiang, Xinmin Wang, Q. Wen, Pingwen Zhang
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引用次数: 15

Abstract

Emerging infectious diseases are existential threats to human health and global stability. The recent outbreaks of the novel coronavirus COVID-19 have rapidly formed a global pandemic, causing hundreds of thousands of infections and huge economic loss. The WHO declares that more precise measures to track, detect and isolate infected people are among the most effective means to quickly contain the outbreak. Based on trajectory provided by the big data and the mean field theory, we establish an aggregated risk mean field that contains information of all risk-spreading particles by proposing a spatio-temporal model named HiRES risk map. It has dynamic fine spatial resolution and high computation efficiency enabling fast update. We then propose an objective individual epidemic risk scoring model named HiRES-p based on HiRES risk maps, and use it to develop statistical inference and machine learning methods for detecting suspected epidemic-infected individuals. We conduct numerical experiments by applying the proposed methods to study the early outbreak of COVID-19 in China. Results show that the HiRES risk map has strong ability in capturing global trend and local variability of the epidemic risk, thus can be applied to monitor epidemic risk at country, province, city and community levels, as well as at specific high-risk locations such as hospital and station. HiRES-p score seems to be an effective measurement of personal epidemic risk. The accuracy of both detecting methods are above 90\% when the population infection rate is under 20\%, which indicates great application potential in epidemic risk prevention and control practice.
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利用轨迹大数据检测疑似疫情
新出现的传染病是对人类健康和全球稳定的生存威胁。最近,新型冠状病毒肺炎疫情迅速形成全球大流行,造成数十万人感染,造成巨大经济损失。世卫组织宣布,更精确的追踪、检测和隔离感染者的措施是迅速控制疫情的最有效手段之一。基于大数据提供的轨迹和平均场理论,我们通过提出一个名为HiRES风险图的时空模型,建立了一个包含所有风险扩散粒子信息的聚合风险平均场。它具有动态精细的空间分辨率和高计算效率,能够快速更新。然后,我们提出了一个客观的个人流行病风险评分模型HiRES-p,并使用它来开发统计推断和机器学习方法来检测疑似流行病感染的个体。我们将提出的方法应用于数值实验,研究了COVID-19在中国的早期爆发。结果表明,HiRES风险图具有较强的全球趋势和局部变异能力,可用于国家、省、市和社区各级以及医院、车站等特定高危地点的疫情风险监测。HiRES-p评分似乎是衡量个人流行病风险的有效指标。在人群感染率低于20%的情况下,两种检测方法的准确率均在90%以上,在疫情风险防控实践中具有较大的应用潜力。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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