Microdosing psychedelics – Does it have an impact on emodiversity?

IF 2.2 Q3 PHARMACOLOGY & PHARMACY Journal of Psychedelic Studies Pub Date : 2023-01-17 DOI:10.1556/2054.2022.00208
I. Pop, Jannis Dinkelacker
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引用次数: 1

Abstract

Previous research has proposed that microdosing, i.e., the repeated use of sub-threshold doses of serotonergic hallucinogens, has an impact on mood by increasing emotional awareness. We propose that increased emotional awareness could translate into higher emodiversity, a balanced experience of emotions in which emotions are experienced with more similarity in intensity and duration. We examine the effect of microdosing, the day after, as well as the cumulative effect of microdosing on overall, positive and negative emodiversity.We use data collected over a period of 28 days sampled between February to June 2020 from 18 users that already had an active practice of microdosing at the start of the data collection. We assessed emotional states using ESM methods, i.e., signal-contingent sampling with triggers sent 5 times a day. The working dataset has a number of 224 observations days. We used mixed effects models to test our hypotheses.When taking into account the level of average affect, we found that during microdosing days positive and overall emodiversity were significantly lower. No evidence was found for a mediating role of the level of average affect. Higher cumulative instances of microdosing were not related to any of the emodiversity indexes. Participants experienced more “awe, wonder, or amazement”, “ashamed, humiliated, or disgraced” as well as less “joyful, glad, or happy” emotions during microdosing days.A microdosing practice may increase the centrality of certain emotions on microdosing days, resulting in a decrease in emotional diversity.
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微量迷幻药——它对情绪多样性有影响吗?
先前的研究表明,微量给药,即重复使用低于阈值剂量的5-羟色胺能致幻剂,通过提高情绪意识对情绪产生影响。我们提出,情绪意识的增强可以转化为更高的情绪多样性,这是一种平衡的情绪体验,在这种体验中,情绪在强度和持续时间上更相似。我们研究了第二天微量给药的影响,以及微量给药对整体、积极和消极情绪多样性的累积影响。我们使用了在2020年2月至6月期间28天内从18名用户那里收集的数据,这些用户在数据收集开始时就已经有了积极的微剂量实践。我们使用ESM方法评估情绪状态,即每天发送5次触发信号的随机抽样。工作数据集的观测天数为224天。我们使用混合效应模型来检验我们的假设。当考虑到平均情绪水平时,我们发现在微量给药期间,阳性和整体情绪多样性显著降低。没有发现任何证据表明平均情感水平具有中介作用。微量给药的累积次数较高与任何情绪多样性指数无关。在微剂量的日子里,参与者体验到更多的“敬畏、惊讶或惊讶”、“羞愧、羞辱或丢脸”,以及更少的“快乐、高兴或快乐”情绪。微剂量练习可能会在微剂量日增加某些情绪的中心性,导致情绪多样性降低。
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来源期刊
Journal of Psychedelic Studies
Journal of Psychedelic Studies Social Sciences-Anthropology
CiteScore
2.50
自引率
8.90%
发文量
20
审稿时长
26 weeks
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