{"title":"A Study Never Proves Anything: Contemporary Interpretation of the Levels of Clinical Evidence and Statistical Significance.","authors":"Andrew J Meyr","doi":"10.1016/j.cpm.2023.07.003","DOIUrl":null,"url":null,"abstract":"<p><p>Critical analysis of the medical literature and an evidence-based approach to clinical practice and medical decision-making is of vital importance in contemporary podiatric practice. This article reviews the levels of clinical evidence and their application within this paradigm. This includes determining which level of evidence is most appropriate for a given methodology, as well as an appreciation of inherent limitations within each level of evidence. The article concludes with a discussion on the difference between statistical significance and clinical significance.</p>","PeriodicalId":48939,"journal":{"name":"Clinics in Podiatric Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in Podiatric Medicine and Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.cpm.2023.07.003","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/8/12 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Critical analysis of the medical literature and an evidence-based approach to clinical practice and medical decision-making is of vital importance in contemporary podiatric practice. This article reviews the levels of clinical evidence and their application within this paradigm. This includes determining which level of evidence is most appropriate for a given methodology, as well as an appreciation of inherent limitations within each level of evidence. The article concludes with a discussion on the difference between statistical significance and clinical significance.
期刊介绍：
Each issue of Clinics in Podiatric Medicine and Surgery updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in podiatry and is presented under the direction of an experienced editor. Topics include charcot foot, the diabetic foot, imaging, pain management, ankle arthritis, foot and ankle arthroscopy, bunions, athletic injuries, wound and bone healing, fractures, dislocations, sprains, torn ligaments, amputations, infections, tumors, congenital deformities, and joint destruction.
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