Supportive medications and interventions received by prostate cancer survivors: results from the PiCTure study

F. Drummond, A. Gavin, L. Sharp
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引用次数: 3

Abstract

Prostate cancer treatments are associated with various physical after-e ects, including urinary, sexual, and bowel symptoms.1 ese after-e ects can have an impact on survivors’ healthrelated quality of life (HRQoL).2 Pharmaceutical and surgical interventions are available to manage or ameliorate many of these after-e ects (eg, sildena…l citrate taken during and after radiotherapy improves sexual function),3 and their receipt has a positive impact on HRQoL.4 However, studies of clinicians suggest that such interventions may not be used widely.5,6 Patientreported data on this topic is lacking. erefore, we investigated the use of supportive medications and interventions in this population-based study of prostate cancer survivors. Methods e PiCTure (Prostate Cancer Treatment, Your Experience) study methods have been described elsewhere.7 BrieŽy, 6,559 prostate cancer survivors 2-15 years after diagnosis (diagnosed during January 1, 1995-March 31, 2010, and alive in November 2011), identi…ed from population-based cancer registries in the Republic of Ireland and Northern Ireland, were invited to complete a postal survey. Information was sought on after-e ects (incontinence, impotence, gynaecomastia, hot Žashes/sweats, bowel problems, depression) that had been experienced at any time after treatment. For each after-e ect, men were asked if they had received any medication or interventions to alleviate symptoms, and, if so, what they had received; examples of common interven-
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前列腺癌幸存者接受的支持性药物和干预:来自PiCTure研究的结果
前列腺癌症治疗与各种生理后果相关,和肠道症状。1这些后遗症会对幸存者的健康相关生活质量(HRQoL)产生影响。2药物和外科干预措施可用于管理或改善许多后遗症(例如,在放疗期间和放疗后服用枸橼酸西地那可改善性功能),3并且它们的服用对HRQoL有积极影响。4然而,临床医生的研究表明,这种干预措施可能不会被广泛使用。5,6缺乏关于这一主题的患者分析数据。因此,我们调查了支持性药物和干预措施在这项基于人群的癌症幸存者研究中的应用。方法e PiCTure(前列腺癌症治疗,您的经验)研究方法已在其他地方描述。7 Brie y,6559名前列腺癌症幸存者,诊断后2-15年(1995年1月1日至2010年3月31日诊断,2011年11月存活),来自爱尔兰共和国和北爱尔兰基于人口的癌症登记处,被邀请完成邮寄调查。寻求治疗后任何时候出现的后遗症(失禁、阳痿、女性昏迷、热灰/出汗、肠道问题、抑郁症)的信息。对于每个后遗症,男性被问及是否接受过任何缓解症状的药物或干预措施,如果接受了,他们接受了什么;共同干预的例子-
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