Linfoma de Hodgkin durante el embarazo: reporte de un caso

Carlos Reyna-Castelán, Sandra Nayeli Robledo-Márquez, Dafne Andrea López-Salazar
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Abstract

BACKGROUND: Hodgkin lymphoma during pregnancy accounts for 4 th place in the neoplasms. Pregnancy has no impact on the natural history of the disease; however, it hinders treatment, which is individualized from a clinical evaluation and based on staging. CLASSIC CASE: Patient 18 years of age, with pregnancy of 35 weeks gestation, who is referred to the external consultation of Oncology Gynecology by increased volume in right axillary region with deep palpation pain. During its examination presence of 3 x 3.5 cm mobile node, on the right side of the axillary region, and left inguinal adenopa-thy >1 cm. The ultrasound reported right breast with solid mass, homogeneous, sharp edges, 38 x 35 mm and volume of 20.84 cc, doppler color with increased vascularity, is staged as BIRADS 3. Cesarean section was performed, with male birth, weight; 2900 g Apgar 8/9 without incident report. In the periareolar excisional biopsy, eight axillary lymph nodes were removed. Immunohistochemistry confirmed a classic LH-compatible lymphoproliferative process with CD30+, KI67 50% mixed cellularity. The hematology service decides management based on chemotherapy with ABVD protocol in 6 blocks, without radiotherapy. Currently it is evolving smoothly after six months of surgery, there was no corroborate of palpable nodes, and so far treatment, without reports of relapses or reaction to medications.
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妊娠期霍奇金淋巴瘤1例
背景:妊娠期霍奇金淋巴瘤在肿瘤中占第4位。妊娠对疾病的自然史没有影响;然而,它阻碍了根据临床评估和分期进行个性化治疗。典型病例:患者18岁,妊娠35周,因右腋窝体积增加伴深部触诊疼痛而转诊至妇科肿瘤科外部会诊。在检查过程中,腋窝右侧有3 x 3.5 cm的活动淋巴结,左侧腹股沟腺癌厚度>1 cm。超声报告右侧乳房肿块实性,均匀,边缘锋利,38 x 35 mm,体积20.84 cc,多普勒彩色,血管增加,分期为BIRADS 3。剖宫产,产男,体重;2900g Apgar 8/9,无事故报告。在乳晕周围切除活组织检查中,切除了8个腋窝淋巴结。免疫组织化学证实了典型的LH相容性淋巴增生过程,CD30+,KI67 50%混合细胞。血液学服务部门决定在6个区块采用ABVD方案进行化疗的基础上进行管理,不进行放射治疗。目前,经过六个月的手术,它进展顺利,没有可触及的淋巴结的证实,到目前为止,也没有治疗,也没有复发或药物反应的报告。
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来源期刊
Ginecologia y obstetricia de Mexico
Ginecologia y obstetricia de Mexico Medicine-Obstetrics and Gynecology
CiteScore
0.20
自引率
0.00%
发文量
107
期刊介绍: Indizada en: Artemisa, Embase Cd/Obstetrics and Gynecology, Embase. Co/Pediatrics, Excerfta Médica, Índice Médico Latinoamericano, Lulacs, Medline, Science Citation Index, Ulrich, Ebsco.
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