Cardiac pleomorphic sarcoma after placement of Dacron graft

Monaliben Patel
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Abstract

Primary cardiac tumors, either benign or malignant, are very rare. e combined incidence is 0.002% on pooled autopsy series.1 e benign tumors account for 63% of primary cardiac tumors and include myxoma, the most common, and followed by papillary broelastoma, broma, and hemangioma. e remaining 37% are malignant tumors, essentially predominated by sarcomas.1 Although myxoma is the most common tumor arising in the left atrium, we present a case that shows that sarcoma can also arise from the same chamber. In fact, sarcomas could mimic cardiac myxoma.2 e cardiac sarcomas can have similar clinical presentation and more importantly can share similar histopathological features. Sarcomas may have myxoid features.2 Cases diagnosed as cardiac myxomas should be diligently worked up to rule out the presence of sarcomas with myxoid features. In addition, foreign bodies have been found to induce sarcomas in experimental animals.3,4 In particular, 2 case reports have described sarcomas arising in association with Dacron vascular prostheses in humans.5,6 We present here the case of a patient who was diagnosed with cardiac pleomorphic sarcoma 8 years after the placement of a Dacron graft.
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涤纶移植物植入后的心脏多形性肉瘤
原发性心脏肿瘤,无论是良性还是恶性,都非常罕见。合并尸检系列的e综合发病率为0.002%。1e良性肿瘤占原发性心脏肿瘤的63%,包括最常见的粘液瘤,其次是乳头状弹性纤维瘤、纤维瘤和血管瘤。e其余37%为恶性肿瘤,主要以肉瘤为主。1尽管粘液瘤是左心房最常见的肿瘤,但我们提出的一个病例表明,肉瘤也可发生在同一心房。事实上,肉瘤可以模仿心脏粘液瘤。2e心脏肉瘤可以有相似的临床表现,更重要的是可以共享相似的组织病理学特征。肉瘤可能具有黏液样特征。2诊断为心脏黏液瘤的病例应仔细检查,以排除黏液样特征肉瘤的存在。此外,还发现异物会在实验动物中诱发肉瘤。3,4特别是,2例病例报告描述了与人类涤纶血管假体相关的肉瘤。5,6我们在这里介绍了一例患者,该患者在植入涤纶移植物8年后被诊断为心脏多形性肉瘤。
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