Urinary Tract Infections in Patients Admitted to the Nephrology Department

Mouayche Ikhlas, H. Hana, Hiddou Abdesalam, El Assas Hajar, F. Wafaa, L. Inass, Soraa Nabila
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引用次数: 1

Abstract

Urinary infections (UI) remain among the most frequent problems faced by the clinician and occupy a prominent place in nephrological pathology due to their frequency and severity. The aim of this work is to study the aspect of UI in the nephrology service. Materials and methods: This is a prospective study over a periodof 5 months (July 2016 – December 2016). Results: 115 patients had benefited from cytobacterioligical urine exam. The prevalence of UI was 31%. The mean age of patients was 38 years with a female predominance. Renal failure was found in 33% of patients followedby nephrotic syndrome (25%) and kidney transplant (11%). Chronic renal insufficiency was foundin25% of patients and 23% receivedan Endoxanbolus. The mostincri minatedspecies were Enterobacteriae (81%) with the predominance of E. coli (44%) followed by Klebsiella pneumoniae (31%) Enterobacter cloacae (3%) resistance to C3G by production of Betalactamases with extended spectrum was found in 24% of Enterobacteriaceae. Resistance to amoxicillin-clavulanic acidwas 72%, fluoroquinolones (34%) and gentamicin (14%). Thefirst-lineantibioticwas Ciprofloxacinin (62%) and a third generation cephalosporin in 28% of cases. Conclusion: Area soned use of antibiotic sisnecessaryin order to prevent the extension of bacterial resistance.
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肾内科住院患者的尿路感染
尿路感染(UI)仍然是临床医生面临的最常见的问题之一,由于其频率和严重程度,在肾脏病理学中占有重要地位。这项工作的目的是研究UI在肾脏病服务中的作用。材料和方法:这是一项为期5个月(2016年7月至2016年12月)的前瞻性研究。结果:115例患者进行了细胞学尿液检查,UI发生率为31%。患者的平均年龄为38岁,以女性为主。33%的肾病综合征(25%)和肾移植(11%)患者出现肾功能衰竭。25%的患者发现慢性肾功能不全,23%的患者接受了Endoxanbolus治疗。最常见的菌株是肠杆菌科(81%),以大肠杆菌(44%)为主,其次是肺炎克雷伯菌(31%)阴沟肠杆菌(3%),24%的肠杆菌科细菌对C3G产生了扩展谱的β-半乳糖酰胺酶抗性。对阿莫西林-克拉维酸、氟喹诺酮类药物(34%)和庆大霉素(14%)的耐药性为72%。第一类抗生素是环丙沙星(62%)和第三代头孢菌素(28%)。结论:为防止细菌耐药性的扩大,有必要在区域内使用抗生素。
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