B. Bilalodin, Wihantoro Wihantoro, A. Haryadi, F. Abdullatif
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Abstract
The dosimetry analysis of Boron Neutron Capture Therapy (BNCT) on thyroid cancer using the Particle and Heavy Ion Transport Code System (PHITS) has been carried out. The purpose of research was to determine the received dose rate and the irradiation time required for thyroid cancer therapy using the BNCT method. The geometry of thyroid model is based on MIRD phantom with cancer cells located in the center of the thyroid. The phantom was irradiated using a neutron source from DLBSA based 30 MeV cyclotron. Simulations were carried out at boron concentrations of (10, 20, 30, 40, 50, 60, and 70) mg/g tissue. Simulation results show that the boron concentration increases with dose rate. The highest dose rate was obtained in the Gross Target Volume (GTV) of 1.590 x 10-2 Gy/s using a boron concentration of 70 mg/g tissue. The effective time for cancer therapy was calculated based on the highest dose rate obtained at 57 minutes.
利用粒子和重离子传输编码系统（PHITS）对癌症的硼中子捕获治疗（BNCT）进行了剂量测定分析。本研究的目的是用BNCT方法确定甲状腺癌症治疗所需的剂量率和照射时间。甲状腺模型的几何形状基于MIRD体模，癌症细胞位于甲状腺中心。使用来自基于DLBSA的30MeV回旋加速器的中子源照射体模。模拟是在硼浓度为（10、20、30、40、50、60和70）mg/g组织下进行的。模拟结果表明，硼浓度随剂量率的增加而增加。在硼浓度为70 mg/g组织的情况下，在1.590 x 10-2 Gy/s的总靶体积（GTV）下获得了最高剂量率。癌症治疗的有效时间是根据57分钟时获得的最高剂量率计算的。
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