Vaginal delivery after 37 days of a convalescent pregnant woman with COVID-19: a case report/ 中华围产医学杂志

Abstract

We present a case report of a healthy neonate born by vaginal delivery to a woman who had recovered from COVID-19 after 37 days of discharge. The pregnant woman had fever, cough, and chills at 33+1 gestational weeks and was diagnosed with COVID-19 by coronavirus nucleic acid test one day later. She recovered and was discharged after a series of treatments, and the 2019 novel coronavirus nucleic acid test was negative and pulmonary CT was normal at the 2nd and 4th week after being discharged. The patient was admitted due to threatened labor at 38+4 gestational weeks and delivered a healthy newborn vaginally on that day. Both the mother and the baby were in good condition. All the maternal or neonatal specimens taken in the delivery room for 2019 novel coronavirus nucleic acid tests were negative, including the maternal pharynx, rectal and cervical secretions before delivery, amniotic fluid, and colostrum neonatal pharynx and rectal swabs after birth. The qualitative examination of 2019 novel coronavirus antibodies in the maternal venous blood test before delivery showed that both IgG and IgM were positive. While the same test for neonatal cord blood and femoral vein blood showed negative results. No inflammatory reaction was found in the placenta and immunohistochemistry detection of novel coronavirus N protein was negative. The mother and newborn were observed and treated postnatally in the same ward; neither of them had fever, cough, or fatigue, and were discharged three days after delivery. The qualitative examination of 2019 novel coronavirus antibodies (IgM and IgG) in the femoral vein blood of the neonate at 27 days old showed negative results. Key words: Coronavirus infections; Pregnancy complications, infectious; Parturition