Coronary Stenting versus Bypass Graft Surgery for Management of Left Main Coronary Artery Disease in the Setting of Acute Myocardial Infarction: A Retrospective Cohort Study

M. Bordy, W. Kamel, Gamal Abd el hady, Ihab M. Yassin
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Abstract

Background: There is a lack of published research that compare stenting versus coronary artery bypass grafting (CABG) for patients with left main coronary artery (LMCA) disease. This research compared the safety and efficacy of stents versus CABG for patients with LMCA disease in the setting of acute myocardial infarction. Materials and Methods: A retrospective chart review was conducted to retrieve the records of LMCA who underwent coronary stenting or CABG. We compared both techniques in terms of major adverse cardiovascular and cerebrovascular events (MACCE) and postoperative complications. Results: Sixty patients were included (30 patients in each group). The incidence of periprocedural mortality was equal between PCI and CABG groups (6.7% versus 10%). Likewise, the overall incidence of periprocedural complications was comparable between both groups (13.3% versus 20%). The incidence of immediate post procedural complications was 20% and 30% in PCI and CABG groups, respectively (p =0.37). Likewise, the rate of immediate post procedural mortality was 3.3% and 6.7%, respectively (p =1.0). Both groups exhibited similar rates of late post procedural complications as well (p =0.25). Conclusion: In conclusion, PCI and CABG had comparable postoperative outcomes in LMCA patients in the setting of acute myocardial infarction. Further randomized controlled trials with larger sample size and longer follow-up period are required to evaluate the safety and efficacy of both techniques in such patients.
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冠状动脉支架与搭桥术治疗急性心肌梗死左主干冠状动脉疾病的回顾性队列研究
背景:对于左主干冠状动脉(LMCA)疾病患者,缺乏已发表的比较支架置入术与冠状动脉旁路移植术(CABG)的研究。本研究比较了支架与冠状动脉旁路移植术在急性心肌梗死情况下治疗LMCA疾病患者的安全性和有效性。材料和方法:进行回顾性图表回顾,以检索接受冠状动脉支架置入术或CABG的LMCA的记录。我们比较了两种技术在主要心血管和脑血管不良事件(MACCE)和术后并发症方面的作用。结果:纳入60例患者(每组30例)。PCI组和CABG组围手术期死亡率相同(6.7%对10%)。同样,两组围手术期并发症的总体发生率相当(13.3%对20%)。PCI组和CABG组术后立即并发症的发生率分别为20%和30%(p=0.37)。同样,术后立即死亡率分别为3.3%和6.7%(p=1.0)。两组术后晚期并发症发生率相似(p=0.25)。结论:总之,在急性心肌梗死的情况下,经皮冠状动脉介入治疗和冠状动脉旁路移植术在LMCA患者中具有可比的术后结果。需要进一步的随机对照试验,具有更大的样本量和更长的随访期,以评估这两种技术在此类患者中的安全性和有效性。
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