Aggressive well differentiated invasive ductal carcinoma twelve years after bilateral mastectomies for invasive lobular carcinoma

F. Khan, R. Zafar, M. F. Lambert, Yasmine Kanaan, T. Naab
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Abstract

Ductal and lobular breast neoplasms represent morphologically distinct entities. Ductal breast carcinoma may involve lobules and lobular carcinoma may involve ducts. Invasive lobular carcinoma is difficult to diagnose on screening mammogram since it often does not form a mass lesion in contrast to ductal breast cancer [13]. It may present as an area of thickening or change in texture [4]. Lobular neoplasia includes atypical lobular hyperplasia, lobular carcinoma in situ (LCIS) and invasive lobular carcinoma.
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侵袭性小叶癌双侧乳腺切除术后12年的侵袭性高分化浸润性导管癌
乳腺导管和小叶肿瘤在形态上是不同的实体。乳腺导管癌可能累及小叶,小叶癌可能累及导管。侵袭性小叶癌很难在筛查乳房X光检查中诊断,因为与癌症相比,它通常不会形成肿块[13]。它可能表现为增厚或质地变化的区域[4]。小叶瘤变包括不典型小叶增生、小叶原位癌(LCIS)和浸润性小叶癌。
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