{"title":"MODEL FOR TRANSMISSION AND OPTIMAL CONTROL OF ANTHRAX INVOLVING HUMAN AND ANIMAL POPULATION","authors":"A. Zewdie, S. Gakkhar, Shivmurti K Gupta","doi":"10.1142/s0218339022500218","DOIUrl":null,"url":null,"abstract":"Anthrax is a disease caused by Bacillus anthracis, commonly affects animals as well as humans health. In this paper, a nonlinear deterministic anthrax model involving human and animal is proposed and analyzed. The reproduction number [Formula: see text] and equilibrium points are explored to study the dynamic behavior of the disease. The existence and stability of equilibrium points are discussed. For [Formula: see text], the disease-free equilibrium [Formula: see text] is globally stable. However, it is unstable when [Formula: see text] and a locally stable endemic equilibrium point [Formula: see text] exists. The model is then extended to optimal control model considering human vaccination, animal vaccination and proper removal of carcass. The vaccination class of human and animal population appears separately in a model. The existence and characterization of optimal control are discussed. The numerical simulations are carried out for the choice of parametric values and initial conditions. These illustrate scavengers in the suspected area which eat infected dead body of animals contributing to the effort of reducing the expansion of disease. In addition, numerical comparison analysis with four distinct control strategies is carried out. Our findings show that each control technique has its own influence on reducing the total number of infections in the human and animal populations. The cumulative impact of all control measures is found to be extremely effective in lowering the prevalence of the disease.","PeriodicalId":54872,"journal":{"name":"Journal of Biological Systems","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biological Systems","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1142/s0218339022500218","RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Anthrax is a disease caused by Bacillus anthracis, commonly affects animals as well as humans health. In this paper, a nonlinear deterministic anthrax model involving human and animal is proposed and analyzed. The reproduction number [Formula: see text] and equilibrium points are explored to study the dynamic behavior of the disease. The existence and stability of equilibrium points are discussed. For [Formula: see text], the disease-free equilibrium [Formula: see text] is globally stable. However, it is unstable when [Formula: see text] and a locally stable endemic equilibrium point [Formula: see text] exists. The model is then extended to optimal control model considering human vaccination, animal vaccination and proper removal of carcass. The vaccination class of human and animal population appears separately in a model. The existence and characterization of optimal control are discussed. The numerical simulations are carried out for the choice of parametric values and initial conditions. These illustrate scavengers in the suspected area which eat infected dead body of animals contributing to the effort of reducing the expansion of disease. In addition, numerical comparison analysis with four distinct control strategies is carried out. Our findings show that each control technique has its own influence on reducing the total number of infections in the human and animal populations. The cumulative impact of all control measures is found to be extremely effective in lowering the prevalence of the disease.
期刊介绍:
The Journal of Biological Systems is published quarterly. The goal of the Journal is to promote interdisciplinary approaches in Biology and in Medicine, and the study of biological situations with a variety of tools, including mathematical and general systems methods. The Journal solicits original research papers and survey articles in areas that include (but are not limited to):
Complex systems studies; isomorphies; nonlinear dynamics; entropy; mathematical tools and systems theories with applications in Biology and Medicine.
Interdisciplinary approaches in Biology and Medicine; transfer of methods from one discipline to another; integration of biological levels, from atomic to molecular, macromolecular, cellular, and organic levels; animal biology; plant biology.
Environmental studies; relationships between individuals, populations, communities and ecosystems; bioeconomics, management of renewable resources; hierarchy theory; integration of spatial and time scales.
Evolutionary biology; co-evolutions; genetics and evolution; branching processes and phyllotaxis.
Medical systems; physiology; cardiac modeling; computer models in Medicine; cancer research; epidemiology.
Numerical simulations and computations; numerical study and analysis of biological data.
Epistemology; history of science.
The journal will also publish book reviews.