Antioxidant and antibacterial efficacy of Chaetomorpha linum and its toxicological evaluation for the prophylactic treatment against Pseudomonas aeruginosa infection in Labeo rohita
S. Thanigaivel, John Thomas, A. Vickram, G. Gulothungan, R. Nanmaran, D. Jenila Rani
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引用次数: 1
Abstract
ABSTRACT The antioxidant activity and antibacterial efficacy of aqueous and ethanolic extracts of Chaetomorpha linum were tested against bacterial infection caused by Pseudomonas aeruginosa. In vitro and in vivo studies revealed the efficacy of ethanolic extract of C. linum in controlling the P. aeruginosa infection. Gas Chromatography Mass Spectroscopy analysis of purified fractions of ethanolic extract was also performed. Ichthyotoxic bioassay of purified seaweed extracts was performed to assess its toxic effect in rohu fish and found to be nontoxic. Experimental pathogenicity of P. aeruginosa showed exophthalmia, reduced intake of feed, and lesions on the body. LD 50 was achieved at the 3.96 × 102 at 48 h and 4.82 × 103 at 72 h in the experimental pathogenicity. The results revealed that the ethanolic extract of C. linum can be used as an alternate source for controlling P. aeruginosa infection in L. rohita.
期刊介绍：
The Journal of Applied Aquaculture is a platform for the sharing of practical information needed by researchers to meet the needs of investors, farm managers, extension agents and policy makers working to adapt aquaculture theory to achieve economic and food security objectives in the real world. The journal emphasizes multi-disciplinary research and case studies that propose financially and logistically viable solutions to observable problems.
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