{"title":"The Human Gene Editing Debate","authors":"T. Stammers","doi":"10.1080/20502877.2022.2117516","DOIUrl":null,"url":null,"abstract":"(p. 21) − The drug Ivacaftor, used as a treatment for cystic fibrosis, does not ‘produce the missing [CFTR] protein’ (as stated by Professor David Packham, Leeds University). The drug is a complex phenolic compound that binds to the defective channel protein, forcing the ion channel to open (p. 24) − Heritable genome editing is currently achieved by editing the genome of the zygote (one-cell embryo) not the eggs and sperm. The eggs or sperm produced by the adult that develops from the zygote will carry the edit (p. 49) − HIV is not a heritable disease (p.50) − Malaria is not caused by a virus but by a mosquito-transmissible protist. (p. 93)","PeriodicalId":43760,"journal":{"name":"New Bioethics-A Multidisciplinary Journal of Biotechnology and the Body","volume":"29 1","pages":"77 - 80"},"PeriodicalIF":1.4000,"publicationDate":"2022-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"New Bioethics-A Multidisciplinary Journal of Biotechnology and the Body","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/20502877.2022.2117516","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ETHICS","Score":null,"Total":0}
引用次数: 0
Abstract
(p. 21) − The drug Ivacaftor, used as a treatment for cystic fibrosis, does not ‘produce the missing [CFTR] protein’ (as stated by Professor David Packham, Leeds University). The drug is a complex phenolic compound that binds to the defective channel protein, forcing the ion channel to open (p. 24) − Heritable genome editing is currently achieved by editing the genome of the zygote (one-cell embryo) not the eggs and sperm. The eggs or sperm produced by the adult that develops from the zygote will carry the edit (p. 49) − HIV is not a heritable disease (p.50) − Malaria is not caused by a virus but by a mosquito-transmissible protist. (p. 93)
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